Immune Responses in Chronic Diseases, Crucial Molecular Mechanisms, and Microenvironmental Factors
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Biology".
Deadline for manuscript submissions: closed (31 March 2022) | Viewed by 3788
Special Issue Editor
Special Issue Information
Dear Colleagues,
The clinical consequences of immune failure primarily include increased susceptibility to infections and reduced response to vaccination. However, malfunction of immune system reactivity is also a reason for higher susceptibility to chronic diseases such as malignant tumors, autoimmune and neurodegenerative diseases. The mechanisms that cause immune changes in chronic diseases are still poorly understood. Many detrimental changes have roots at the molecular level and include DNA damage, microenvironmental factors including epigenetic changes, as well as disturbed intercellular interactions. Such molecular changes have a multidirectional character, and those visible in populations of white blood cells directly affect initiation and progression of chronic diseases. This Special Issue will survey crucial molecular mechanisms and microenvironmental factors associated with immune responses in chronic diseases.
Prof. Dr. Agata Matejuk
Guest Editor
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Keywords
- immune response
- chronic diseases
- cancer
- autoimmunity
- neurodegeneration
