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Special Issue "The Influence of Pre- and Post-ingestive Signals in Sensory Perception and Food Intake"

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Bioactives and Nutraceuticals".

Deadline for manuscript submissions: 28 February 2022.

Special Issue Editors

Prof. Dr. Fernando Capela e Silva
E-Mail Website
Guest Editor
Department of Biology, School of Sciences and Technology and Institute of Mediterranean Agricultural and Environmental Sciences (ICAAM), University of Évora, Évora, Portugal
Interests: comparative animal histology and cytology tissues homeostasis and biomarkers of tissue function; injury and repair; oral biology
Special Issues and Collections in MDPI journals
Dr. Elsa Lamy
E-Mail Website1 Website2
Guest Editor
Institute for Agriculture, Environment and Development - MED, University of Évora, Évora, Portugal
Interests: biological factors influencing food choices; saliva proteomics; salivary glands regulation; food perception; oral biology
Special Issues and Collections in MDPI journals
Prof. Dr. Cláudia Viegas
Guest Editor
Dietetics and Nutrition Department, Lisbon School of Health Technology (ESTeSL), Polytechnique Institute of Lisbon, Lisbon, Portugal
Interests: health promotion; nutrition and lifestyle; applied nutrition in gastronomy and food service; eating behavior

Special Issue Information

Dear Colleagues,

Nutritional and health status are greatly dependent on the type of foods chosen and the amounts eaten. This, in turn, is greatly dependent on the way individuals perceive sensory characteristics of foods. It is known that the control of food choices and appetite is based on a complex set of interactions including psychological events, central nervous system (CNS) signals, metabolic events and peripheral physiology, as well as the interactions of these last in the CNS. Sensory signals act as pre-ingestive indicators of food quality, preparing the body for the subsequent entry of food. These signals can interact with each-other, modulating final perception and intake. This multisensory interplay is particularly important, as for example, visual cues can result in changes in taste perception, or even in changes in appetite sensation. At the same time, post-ingestive and post-absorptive signals are known to exert a major effect in satiety and satiation, which, in turn, can influence palatability, promoting or inhibiting food overconsumption. Several diseases related with nutrition can be the cause or the consequence of unhealthy food choices, so understanding the interaction between sensory and metabolic signals is of the greatest interest in order to achieve food and nutritional security.

This special issue aims to bring together high-quality research, highlighting the importance of the different pre- and post-ingestive and post-absoptive signals in sensory perception and food intake. The submission of new original research or reviews about this thematic is welcomed. Potential topics include but are not limited to the following:

  • Changes in gastrointestinal peptides and hormones (post-ingestive signals) in response to food pre-ingestive signals.
  • The influence of gastrointestinal peptides and hormones in food perception, appetite and intake.
  • Changes in the effects of pre- and/or post-ingestive signals in health and disease (obesity, diabetes, etc).
  • The Role of the Sweet Taste Receptor in Enteroendocrine Cells and Pancreatic β-Cells.
  • Expression of the sweet receptor protein, T1R3, in the human liver and pancreas.
  • Expression of taste receptors in the gastrointestinal tract and other tissues
  • Role of gut nutrient sensing in stimulating appetite and conditioning food preferences.
  • Taste receptors in the gastrointestinal tract and other organs/tissues.
  • The effect of pre-ingestive signals in oral medium composition.
  • Salivary proteins and orosensory and postingestive feedback.
  • Changes in food acceptance in response to food pre- or post-ingestive signals.
  • Influences of food sensory signals in food choices, food intake and nutritional status.
  • Food texture and the satiety cascade.
  • Relationship between food sensory characteristics and post-ingestive signals.
  • Post-ingestive positive controls of ingestive behavior.
  • Olfactory and taste changes after bariatric surgery.
  • Potential mechanisms underlying the effect of bariatric surgery on eating behaviour.
  • Satiety and energy intake after single and repeated exposure to gel-forming dietary fiber: post-ingestive effects.
  • Flavor preferences conditioned by postingestive effects of nutrients

Prof. Dr. Fernando Capela e Silva
Dr. Elsa Lamy
Prof. Dr. Cláudia Viegas
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • pre- and post-ingestive signals
  • sensory perception
  • food intake
  • nutrients
  • taste receptor

Published Papers

This special issue is now open for submission.
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