Molecular Mechanisms of Ion Transport across Cell Membranes
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Biochemistry".
Deadline for manuscript submissions: closed (30 April 2023) | Viewed by 1897
Special Issue Editor
Interests: sodium bicarbonate transporter; molecular mechanism; structure-function; ion selectivity; alcoholism; addiction
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Ion transporters play vital roles in a variety of cell functions, such as ion gradients across cell membranes, regulation of chemical signals, pH homeostasis, and solute absorption and secretion. The function, localization, and regulation of various ion transporters have been studied in detail, and their roles in tissue or organ physiology have also been examined. The current information on the cellular and functional properties of transporters is well documented, although some variability exists depending upon types of ion transporters. Moreover, structure function analysis, mutagenesis studies, and molecular modeling have identified specific residues and domains that contribute to molecular functional properties, such as ion binding sites, selectivity, and translocation. Crystallography and molecular dynamics simulations have provided new insights into the detailed structure of many transporters. This Special Issue focuses on the current progress in the molecular mechanism of ion transport across cell membranes. The topics include how ions are bound to the binding sites, selected, and translocated via transporters. These topics will be particularly appealing to those interested in specific attention toward clinical and therapeutic aspects of ion transporters. The topic is open to articles and reviews, ranging from molecular levels to cellular and integrated levels.
Dr. Inyeong Choi
Guest Editor
Manuscript Submission Information
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Keywords
- ion transporter
- molecular mechanism
- binding
- selectivity
- translocation
