Special Issue "Kinase Signal Transduction"
Deadline for manuscript submissions: closed (30 September 2016).
Interests: kinase signal transduction; MAP kinase signaling; stress response; ubiquitination; post-translational modifications; redox signaling; cell death; innate immunity; inflammasome; cancer; drug toxicity
Special Issues, Collections and Topics in MDPI journals
Special Issue in International Journal of Molecular Sciences: Kinase Signal Transduction 2019
Special Issue in International Journal of Molecular Sciences: Kinase Signal Transduction 2020
Special Issue in International Journal of Molecular Sciences: Kinase Signal Transduction 2021
Protein kinases phosphorylate a wide variety of substrates, the phosphorylation of which changes their conformation, activity, stability, intracellular localization, and affinity to other molecules. Therefore, protein kinases are critical for various biological functions and cellular processes, such as signal transduction, transcription, protein degradation, vesicle transport, cell growth and death, stress response, immunoregulation, and metabolism. Various types of protein kinases and their regulators have been identified and play a pivotal role in the determination of cell fate. Disregulation of the protein kinase signal transduction leads to various diseases, including cancer, inflammation, autoimmune disorder, neurodegeneration, heart failure, ischemia, and diabetes, indicating that protein kinases and their regulators are important therapeutic targets for these diseases. Thus, understanding of how protein kinases respond to stimuli and regulate cellular functions is crucial both biologically and clinically. This Special Issue, “Kinase Signal Transduction”, welcomes contributions in all areas of recent and current research associated with novel physiological and pathological functions and regulatory mechanisms of protein kinases, as shown above.
Prof. Dr. Atsushi Matsuzawa
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.
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