Special Issue "Non-coding RNAs: Promising Targets in Regenerative Medicine and Cell Therapies"
Deadline for manuscript submissions: 31 December 2021.
2. Pediatric Research Center "Romeo ed Enrica Invernizzi", University of Milan, Milan, Italy
Interests: cell therapies for neurodegenerative disease (Spinal cord injury, Parkinson’s disease); molecular mechanisms of neuronal degeneration and regeneration (epigenetic and non-coding RNA); organoids; 3D culture systems; mechanotransduction and pluripotency; neural stem cells; mesenchymal stem cells; lncRNAs in stemness and differentiation
Special Issues and Collections in MDPI journals
Interests: lncRNAs; stem cells biology; neurodegenerative diseases; molecular mechanisms of neuronal degeneration and regeneration (epigenetics and non-coding RNA); transcriptional profiling of diseases conditions
Long non-coding RNAs (lncRNAs) are RNA molecules longer than 200 bp, with multiple functions in both physiological and diseases-related processes. These molecules present gene expression regulatory abilities, although their role is not limited to this function. Several well-studied examples of lncRNAs suggest that they can operate through distinct modes, including working as signals, scaffolds for protein–protein interactions, molecular decoys, and guides to target elements in the genome or transcriptome. Extensive research is now focused on the full characterization of lncRNAs in multiple biological processes, as they require interdisciplinary studies due to their numerous possible functions. More and more evidence is highlighting fundamental roles for lncRNAs in stem cells renewal and differentiation, along with their potential disruption when these processes are impaired. LncRNAs could thus become new key targets in regenerative medicine and cell therapies, and their study in stem cells is thus fundamental. Moreover, lncRNAs are being investigated and evaluated for clinical use as possible innovative pharmacological treatments. In this Special Issue, we expect to collect both original research and review articles aimed at assessing key advancements in lncRNA’s role as potential therapeutic targets.
Dr. Stephana Carelli
Dr. Federica Rey
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- Long non-coding RNAs
- Stem cells
- Neurodegenerative diseases
- Cellular transcriptome
- Regenerative medicine
- Cell differentiation
- Drug development