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Special Issue "Metabolic Bone Diseases: Molecular Biology, Pathophysiology and Therapy 2.0"

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Endocrinology and Metabolism".

Deadline for manuscript submissions: closed (31 August 2021).

Special Issue Editor

Dr. Agostino Gaudio
E-Mail Website
Guest Editor
Department of Clinical and Experimental Medicine, University of Catania, 95123 Catania, Italy
Interests: osteoporosis; metabolic bone diseases; hypovitaminosis D-related disorders; rare bone diseases; metabolic link between atherosclerosis and bone metabolism
Special Issues and Collections in MDPI journals

Special Issue Information

Dear Colleagues,

Identification of the mechanisms underlying the pathophysiology and therapies of metabolic bone diseases continues to be an area of significant research, attracting scientists from a variety of different fields. The discovery of the Wnt signal and the OPG/Rankl system has contributed significantly to the design and development of new drugs and molecules for the treatment of osteoporosis and other metabolic bone diseases.

For this Special Issue, we invite authors to submit manuscript research and review papers targeting the gamut of methodological and scientific innovation in this field. Of specific interest are papers focused on the discovery of novel drug targets, signaling pathways, and mechanisms of action relevant to metabolic bone diseases. These contributions can involve basic science and translational research or be highly focused on research models related to specific conditions like drug-induced bone loss or other secondary forms of osteoporosis or rare metabolic bone diseases.

Dr. Agostino Gaudio
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • bone metabolism
  • Wnt signaling
  • OPG/Rankl system
  • osteoblast
  • osteoclast
  • osteoporosis

Related Special Issue

Published Papers

There is no accepted submissions to this special issue at this moment.
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