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Special Issue "Recent Advances in Molecular Research of Metabolic Disorders"

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Biochemistry".

Deadline for manuscript submissions: 31 July 2021.

Special Issue Editors

Prof. Dr. Maria S Fernandez-Alfonso
Guest Editor
Instituto Pluridisciplinar and Facultad de Farmacia, Universidad ComplutenseMadrid, Spain
Special Issues and Collections in MDPI journals
Dr. Marta Gil-Ortega
Guest Editor
Department of Pharmaceutical and Health Sciences, San Pablo CEU University, Ctra. Boadilla del Monte Km5.300, 28925-Alcorcón, Spain
Interests: Obesity; blood pressure
Special Issues and Collections in MDPI journals

Special Issue Information

Dear Colleagues,

Nowadays, metabolic disorders are considered to be a major health problem affecting a huge percentage of the population worldwide. They are associated with chronic diseases like obesity, diabetes, non-alcoholic fatty liver disease, or cardiovascular alterations, among others, as well as with a higher incidence of all-cause mortality.

For the last few years, a large number of studies have deepened and progressed our knowledge of the molecular mechanisms involved in the development of metabolic disorders. In this regard, special attention has been focused on oxidative stress, inflammation, endoplasmic reticulum stress, alterations on glucose and/or lipid metabolism, insulin resistance, endothelial dysfunction, etc. Nevertheless, further studies are required in order to identify new potential mechanisms implicated in the development of these alterations and/or potential targets (i.e., new adipokines, signaling molecules, exosomes, epigenetic reprogramming, biomarkers, etc.) that could help to develop new strategies and drugs aimed at preventing and/or reversing the complications associated with metabolic disorders.

This Special Issue aims to review current advances in the field of metabolic disorders associated with obesity, diabetes, and non-alcoholic fatty liver and cardiovascular disease, with the purpose of better understanding the pathways involved in these alterations. Contributions to both animal models and/or humans are encouraged so as to shed light on the development of new therapeutic approaches to improve the clinical management of the cardiometabolic complications derived from metabolic disorders.

Prof. Dr. Maria S Fernandez-Alfonso
Prof. Dr. Marta Gil-Ortega
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • obesity
  • diabetes
  • insulin resistance
  • oxidative stress
  • inflammation
  • non-alcoholic fatty liver disease
  • cardiovascular alterations
  • endoplasmic reticulum stress
  • lipids
  • glucose
  • adipokines
  • exosomes
  • epigenetics
  • biomarkers

Published Papers

This special issue is now open for submission.
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