Special Issue "Recent Advances in Metal Based Drugs"
Deadline for manuscript submissions: closed (30 April 2017).
Interests: metal ions in biological systems; (bioinorganic chemistry) study by physiochemical and spectroscopic methods (IR-Raman, UV-Vis, multinuclear and multidimensional NMR, Mössbauer etc and X-ray crystallography) of metalloenzyme models, like thiamine, SOD and others; metal based antitumor drugs, including Pt(II), Ru(II), Sn(IV) etc.; metal interaction with DNA and RNA constituents aminoacids and oligopeptides as enzyme models; metal induced carcinogennesis; thioamide charge transfer complexes of I2 and mechanism of action of antithyroid drugs; biocatalysis
Interests: Crystal Structure; Structure Determination; Material Characterization; Structural Chemistry; Biological Inorganic Chemistry, Antimicrobial compounds; antiproliferative compounds;
Special Issues and Collections in MDPI journals
Special Issue in Molecules: Antimicrobial Materials with Medical Applications
Special Issue in International Journal of Molecular Sciences: Antimicrobial Materials with Medical Applications
This Special Issue of IJMS, entitled “Recent Advances in Metal Based Drugs”, will cover a selection of recent research and review articles in the field of metal based drugs. The use of metals in medicine goes back to antiquity, with various elements, such as arsenic, gold, and iron, being used to treat different ailments. Nowadays, the medicinal uses and applications of metals and metal complexes are of increasing clinical and commercial importance. A reasonable estimate of commercial importance is approaching US $5 billion annually for the whole field.
The ability to recognize, to understand at the molecular level, and to treat diseases caused by inadequate metal-ion function constitutes an important aspect of medicinal bioinorganic chemistry. Diseases such as anemia (iron), asthma (gold and magnesium), bipolar disorder (lithium), diabetes (vanadium), rheumatoid arthritis (gold), stroke (magnesium), tropical diseases (antimony and rhodium), and ulcers (bismuth) can be treated by metal-based drugs. Arguably, the most prominent drug that contains a metal is cisplatin, the most widely used anti-cancer drug. The success of cisplatin in chemotherapy has motivated a large number of studies into the potential for other platinum and other metal (like palladium, silver, tin, antimony, etc.) complexes as anti-tumor drugs.
From the foregoing, the reader of this Special Issue will gain an appreciation of the very real roles metal-based drugs play. In modern medicine, the considerable effort being devoted to the development of novel complexes with greater efficacies and reduced toxic side effects (an inevitable consequence of all chemotherapy) will be appreciated.
Prof. Dr. Sotiris Hadjikakou
Prof. Dr. Nick Hadjiliadis
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- Metal Based Drugs
- Metallotharapeutic Drugs
- Metals in Medicine
- Platinum Complexes as Therapeutic Agents
- Non-platinum Anticancer Agents
- Antibacterial Agents
- Radioimmunoimaging and Radioimmunotherapy
- Metal Based Diagnostic Agents