MicroRNAs and Long Non-coding RNAs in Tumor Microenvironment 2.0
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Oncology".
Deadline for manuscript submissions: closed (15 January 2023) | Viewed by 2700
Special Issue Editor
Interests: microRNAs and long noncoding RNAs in cancer; tumor microenvironment; lung cancer; metastasis
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
The tumor microenvironment is a complex cellular and non-cellular network system that influences tumorigenesis, progression, metastasis, and drug resistance. Cellular components of the tumor microenvironment include tumor cells, cancer-associated fibroblasts, vascular endothelial cells, infiltrated immune cells, etc. Along with the extracellular matrix, cytokines/chemokines, and hypoxic signals, these cellular components interact directly or indirectly to facilitate tumor initiation and progression. A huge body of research shows support for the crucial role played by microRNAs and long-noncoding RNAs in the interaction between tumor cells and the tumor microenvironment, including stromal cells such as cancer-associated fibroblasts and tumor-associated macrophages. Thus, elucidation of the roles of microRNAs and long noncoding RNAs in the tumor microenvironment would establish the foundation for microRNA- or long noncoding RNA-based tumor diagnostic and therapeutic strategies.
This Special Issue of IJMS will cover a selection of recent research topics and current review articles related to the role of microRNAs and long noncoding RNAs in tumor microenvironment. Up-to-date review articles, commentaries and experimental papers are all welcome.
Dr. Young-Ho Ahn
Guest Editor
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Keywords
- tumor microenvironment
- microRNAs
- long noncoding RNAs
- tumor progression metastasis
- cancer-associated fibroblast
- tumor-associated macrophages
- extracellular matrix
