Special Issue "miRNAs in the Era of Personalized Medicine: From Biomarkers to Therapeutics"
Deadline for manuscript submissions: 30 April 2021.
2. Comprehensive Multidisciplinary Endometriosis Unit, Consorcio Hospital General Universitario de Valencia, Valencia, Spain. Av. Tres Cruces, 2. PC: 46014 Valencia, Spain
3. Department of Paediatrics, Obstetrics and Gynaecology, University of Valencia, Valencia, Spain. Av. Blasco Ibáñez, 15. PC: 46010, Valencia, Spain
Interests: endometriosis; gynecological oncology; laparoscopy; minimally invasive surgery; robotic surgery; biomarkers
Interests: endometriosis; gynecological oncology; miRNAs; epigenomics; biomarkers; translational research
Interests: endometriosis; gynecological oncology; microRNAs; stem cells; proteoglycans; extracellular matrix; inflammation
Special Issues and Collections in MDPI journals
Personalized medicine has become a new paradigm for the management of a wide variety of diseases. A decisive factor for its development has been represented by the molecular characterization of tumours, paving the way for the development of risk stratification algorithms, biomarker development and targeted therapies.
miRNAs have attracted a greater interest in the last years as for the characterization of tumour biology. These small non-coding RNAs with regulatory properties have been proven to be deregulated in several pathologies, from benign pathologies as endometriosis or cardiovascular diseases to distinct forms of solid and haematological malignancies. Since a single miRNA might impact in multiple signalling pathways, they might be involved into disease pathophysiology and also might become potential therapeutic targets. Far from the classical miRNA mimic or antimiR approach, new evidences are pointing to targeted DNA methylation of miRNA promoters as a potential therapeutic strategy. Additionally, the discovery of miRNAs in a myriad of human biofluids has paved the way for its implementation as biomarkers of disease.
This Special Issue aims to broad the knowledge about current advances in the field of miRNAs as mechanisms of disease, biomarkers and potential therapeutic targets.
Dr. Juan Gilabert-Estellés
Dr. Josep Marí-Alexandre
Dr. Martin Götte
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- Personalized medicine