Special Issue "The Interplay of Microbiome and Immune Response in Health and Diseases-2nd Edition"
Deadline for manuscript submissions: 30 November 2021.
Interests: immune response; T cells; cancer; microbiota; inflammation; infectious disease; autoimmune diseases
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Increasing evidence suggests that microbiota plays a key role in human physiology, spanning from intestinal to brain activities and directly influencing several molecular pathways. Recent findings indicate how dysbiosis, a disproportion in the composition and organization of microbial populations, could severely impact in the development of different medical conditions (from metabolic to mood disorders), providing new insight for the comprehension of diverse diseases, such as IBD, obesity, asthma, autism spectrum disorders, stroke, diabetes, and cancer. Given that microbial cells in the gut outnumber cells of the host, microbiota influences human physiology functionally and structurally. Microbial metabolites bridge various, even distant, areas of the organism, by way of the immune and hormone system. For instance, it is now clear that the mutual interaction between the gastrointestinal tract and the brain, the so called gut-brain axis, often involves gut microbiota, indicating that the crosstalk between the organism and its microbial residents represents a fundamental aspect of both establishment and maintenance of healthy conditions. Moreover it is crucial to recognize that microbiota is not localized only in the gut. Both commensal and pathogenic organisms populate, beyond the intestinal tract, other organs and tissues (e.g., skin and oral mucosa) of the “host”. This Special Issue will be dedicated to the impact of microbiota on human health physiology and pathology, welcoming all those studies that will help to clarify how microorganisms interact with their hosts, if there are tissue-specific interactions and what are the effects of their presence, absence or imbalance.
Prof. Dr. Amedeo Amedei
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- immune system
- gut-brain axis
- microbial metabolites