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Special Issue "The Association of Gut Microbiome with Pathogenesis in Viral Infection"

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Microbiology".

Deadline for manuscript submissions: 28 February 2022.

Special Issue Editor

Dr. Takeya Tsutsumi
E-Mail Website
Guest Editor
Division of Infectious Diseases, Advanced Clinical Research Center, The Institute of Medical Science, The University of Tokyo, Tokyo, Japan
Interests: HCV; HBV; viral hepatitis; hepatocarcinogenesis; NAFLD; NASH; COVID-19; HIV
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Accumulating data indicate that the altered gut microbiome (dysbiosis) is associated with pathogenesis in many diseases. In the infection of viruses which target not only the gastro-intestinal tract but also other organs, the alteration of the gut microbiome was also demonstrated, and these changes might be associated with pathogenesis, such as disease severity in COVID-19 or the progression of hepatitis in hepatitis B virus infection.

The gut microbiome has been reported to play an important role in maintaining immune homeostasis. Therefore, the viral infection should directly or indirectly affect the gut microbiome, leading to rapid recovery from infection. On the other hand, the virus itself may damage the microbiome associated with the progression of pathogenesis. In addition, it is known that the microbiome is different depending on the backgrounds (such as race or comorbidities) of each person, which might be able to explain the difference of pathogenesis in the same viral infection.

The aim of this Special Issue is to explore the relationship between the alteration of gut microbiome and pathogenesis in various viral infections. Reviews and original research manuscripts covering new insights on this topic will be considered.  

Dr. Takeya Tsutsumi
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • gut microbiome
  • dysbiosis
  • viral infection
  • immune homeostasis
  • pathogenesis

Published Papers

This special issue is now open for submission.
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