Special Issue "Molecular Mechanisms of Sperm Activation"
Deadline for manuscript submissions: 31 December 2021.
Spermatozoa in the testes are still immature, unable to move, and not fertile, even though spermatogenesis and spermiogenesis are completed. After ejaculation or spawning of semen, sperm acquire motility and fertility and can accomplish fertilization. This process is often species-specific in animals characterized by external fertilization and allows successful conspecific fertilization. Sperm activation in many animals including mammals occurs through common molecular mechanisms, whose elucidation is important to distinguish shared pathways of fertilization from species-specific authentication mechanisms.
This Special Issue will focus on the different aspects of sperm activation: initiation and activation of sperm motility, guidance of sperm swimming (including sperm chemotaxis), capacitation and hyperactivation, and induction of the acrosome reaction. It intends to create a platform for up-to-date high-quality publications on sperm activation during fertilization. Studies on the regulation mechanisms of sperm flagellar motility, the role of ion channels such as CatSper in sperm activation, the identification of molecules mediating sperm activation, etc., are welcome. We also welcome articles on applied research based on sperm activation, concerning, for example, livestock breeding, aquaculture technology, and male infertility. We hope that this Special Issue will provide a broad view of spermatology, from basic biology in marine invertebrates to reproductive medicine, fostering new research in reproductive biology areas.
Dr. Manabu Yoshida
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- Sperm motility
- Flagellar beating
- Capacitation and hyperactivation
- Sperm guidance
- Acrosome reaction
- Seminal plasma
- Ovarian fluid
- Sperm-egg interaction