Special Issue "Motile Function of Myosins in Cells and Tissues"
Deadline for manuscript submissions: closed (30 June 2019).
Interests: physiology and biochemistry of skeletal; cardiac and smooth muscle myosins in health and in disease; compartive aspects of physiology and biochemistry of muscle and mechanism of locomotion; primitive; role of myosins in primitive motile systems; such as amoevoid movement; contractile ring formation; and other cellulr motile functions
Special Issues and Collections in MDPI journals
Myosins constitute a large superfamily and perform a variety of motile functions at the tissue and cellular levels. In skeletal, cardiac, and smooth muscles, myosin forms myosin filaments to produce force and motion in muscle via cyclic interaction with actin filaments, coupled with ATP hydrolysis. Skeletal muscle performance can be enhanced through physical training, which has been studied intensively in the research field of exercise physiology. Cardiovascular activity is maintained by the motile function of cardiac and vascular muscles and has been studied widely in relation to cardiovascular diseases. In primitive motile systems, myosins play an essential role in the amoevoid movement of leucocytes, and cell division resulting from the contractile ring formation. While myosins producing the above motile function are called rower myosins due to their asynchronous attachment to, and detachment from, actin filaments, there are many kinds of myosins, which transport substances within the cells of animals, called porter myosins because of their processive motion along actin filaments.
The main purpose of this Special Issue is to give general readers an idea about the current status of research work on the motile function of myosins as well as remaining mysteries to be investigated in future.
Dr. Haruo Sugi
Dr. Susumu Minamisawa
Manuscript Submission Information
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- skeletal muscle myosin
- cardiac muscle myosin
- smooth muscle myosin
- muscular exercise and training effects
- function of porter myosins
- function of myosins in the amoevoid movement and contractile ring formation
- other aspects of myosin function