The Role of Myosins in Cells
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Biology".
Deadline for manuscript submissions: closed (31 May 2022) | Viewed by 9217
Special Issue Editor
Special Issue Information
Dear Colleagues,
The myosin superfamily is a large, diverse group of actin-molecular motor proteins, involved in muscle contraction, cell motility, cytokinesis, phagocytosis, intracellular and membrane trafficking, intra- and intercellular signaling pathways, pathogenesis and cell communication. For instance, Myosin II is required for muscle contraction, Myosin-Ic can regulate lipid rafts, an important cellular structure for cell signaling and pathogen entry. Myosin-Va has been implicated in the transport of exosomes, while Myosin-X induces numerous cellular protrusions, including tunneling nanotubes (TNTs), and is involved in intercellular disease spread. Cell communication is the ability of cells to obtain and release messages from the environment and to adapt based on these environmental cues. The processing of these messages often leads to the activation of multiple intracellular signaling pathways. In addition, cell-to-cell communication is an essential function for single-cell organisms to coordinate with one another or for multicellular organisms during developmental differentiation, growth, cell division, and remodeling of tissues and organs.
In this Special Issue, we especially welcome any research articles that demonstrate the role of Myosins during cellular development, pathogenesis or that shed light on the molecular mechanisms and role that they play in cells by modulating intracellular signaling as well, as their role in cell-to-cell communication via secretory vesicles and/or via membrane bridges and cellular protrusions. The scope of this special issue is broad. Review articles which summarize the current state of the field are also encouraged.
Prof. Dr. Karine Gousset
Guest Editor
Manuscript Submission Information
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Keywords
- Myosins
- Muscle contraction
- Motility processes
- Cytokinesis
- Phagocytosis
- Pathogenesis
- Membrane trafficking
- Cell communication
- Extracellular vesicles
- exosomes
- Tunneling nanotubes
- Membrane bridges
- Intracellular communication
- Intercellular communication
- Cell signaling
