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Special Issue "Molecular Mechanisms of Neuronal Death in Neurodegeneration"

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Neurobiology".

Deadline for manuscript submissions: 31 October 2021.

Special Issue Editors

Prof. Dr. Rickie Patani
E-Mail Website
Guest Editor
The Francis Crick Institute and UCL Queen Square Institute of Neurology, London, UK
Interests: human induced pluripotent stem cell models of disease; neurodegeneration biology; neuropathology; motor neuron disease (ALS); RNA metabolism; astrocyte biology
Special Issues and Collections in MDPI journals
Dr. Andrea Serio
E-Mail Website
Guest Editor
King’s College London & The Francis Crick Institute, London, UK
Interests: Stem cell Modelling; Metabolism; Axonopathies; Imaging; Neural Circuits; Glial-Neuronal Interactions; Neurodegeneration
Special Issues and Collections in MDPI journals

Special Issue Information

Dear Colleagues,

Neurodegeneration comprises a group of devastating and incurable yet demographically inevitable diseases, given our aging population. Archetypal members of this group include Alzheimer’s disease, Parkinson’s disease, motor neuron disease (ALS), and multiple sclerosis. The precise mechanisms by which neurons initially become dysfunctional and ultimately degenerate remain largely unresolved. This Special Issue focuses specifically on molecular mechanisms underlying neurodegenerative diseases, including cell autonomous mechanisms of neuronal subtype selective vulnerability, non-cell autonomous mechanisms of neuronal dysfunction, and molecular and cellular phases of diseases. Original manuscripts and reviews dealing with these issues are most welcome from outstanding experts on the topic.

Prof. Dr. Rickie Patani
Dr. Andrea Serio
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • neurodegeneration
  • neuronal death
  • Alzheimer’s disease
  • Parkinson’s disease
  • motor neuron disease
  • multiple sclerosis
  • neuronal dysfunction

Published Papers

This special issue is now open for submission.
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