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Special Issue "Nutrients and Nitrite"

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Bioactives and Nutraceuticals".

Deadline for manuscript submissions: closed (30 April 2021).

Special Issue Editors

Prof. Jun Kobayashi
E-Mail Website
Guest Editor
Department of Clinical Dietetics and Human Nutrition, Faculty of Pharmaceutical Science, Josai University. 1-1 Keyakidai, Sakado, Saitama, 350-0295, Japan
Interests: molecular biology; physiology; cardiology; pulmonary hypertension; nitric oxide; ischemia/reperfusion injury; crush syndrome
Dr. Isamu Murata
E-Mail Website
Guest Editor
Laboratory of Pharmacotherapeutics and neuropsychopharmacology, Faculty of Pharmacy and Pharmaceutical Sciences, Josai University, Keyakidai 1-1, Sakado, Saitama 350-0295, Japan
Interests: nitric oxide; ischemia/reperfusion injury; crush syndrome
Dr. Kazuo Ohtake
E-Mail Website
Guest Editor
Laboratory of Physiology, Faculty of Pharmaceutical Sciences, Josai University; 1–1 Keyakidai, Sakado, Saitama 350–0295, Japan
Interests: cell physiology; molecular biology; exercise physiology; nitric oxide; omega-3 fatty acids
Dr. Kunihiro Sonoda
E-Mail Website
Guest Editor
Department of Food and Nutritional Environment, College of Human Life and Environment, Kinjo Gakuin University, Nagoya, Japan
Interests: nutrition; nitrite; nitrate; nitric oxide; hypertension; cardiology

Special Issue Information

Dear Colleagues,

Although nitrate and nitrite were previously considered to be inert end products of endogenously produced nitric oxide (NO) in the process of NO oxygenation, they are now known to be physiologically recycled in the blood and tissue to form NO and other bioactive nitrogen oxides. Decreased NO availability, caused by obesity and endothelial dysfunction, might be causally related to the development of lifestyle-related diseases, such as insulin resistance, ischemic heart disease, and hypertension. However, dietary intake of nitrite as a nutrient may compensate NO synthase (NOS)-dependent NO generation through the enterosalivary nitrate-nitrite-NO pathway by transmitting NO activity in various molecular forms, including NO and protein S-nitrosothiols. Potential topics in this special issue may include the above-mentioned metabolic disorders but are not limited to the association of nitrite-mediated NO activity with lifestyle-related diseases. We would also like to extend the concept of this theme to the field of sports and exercise, maternal nutrition, breastfeeding during the perinatal period, and even to infectious diseases, including COVID-19, in which NO-mediated molecular mechanisms may be beneficially involved. In this special issue, we look forward to discussions on the prophylactic and therapeutic effects of nitrite intake as a nutrient in a variety of pathophysiological conditions.

Prof. Jun Kobayashi
Dr. Isamu Murata
Dr. Kazuo Ohtake
Dr. Kunihiro Sonoda
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • nitrate and nitrite
  • nitric oxide (NO)
  • enterosalivary-nitrate-nitrite-NO pathway
  • microbial flora
  • mitochondrial electron transport chain
  • nitrosylation
  • nitrosation
  • ischemia/reperfusion injury
  • oxidative stress
  • crush syndrome
  • breastfeeding
  • lifestyle-related diseases
  • COVID-19

Published Papers

There is no accepted submissions to this special issue at this moment.
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