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Special Issue "Phenolic Compounds Extracted from Plants: Towards the Formulation of New Nutraceuticals"

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Bioactives and Nutraceuticals".

Deadline for manuscript submissions: 30 December 2021.

Special Issue Editor

Special Issue Information

Dear Colleagues,

Phenolic compounds are a vast group of organic molecules characterized by presenting at least one phenol group (C6H6O) in their molecular structure. They are usually synthetized by plants as secondary metabolites with many different functions, from defense to pollinators attraction. Phenolic compounds can be synthetized for different biochemical pathways and thus, they are a highly diverse group from the metabolic and chemical point of view. In this context, it is important to assess the renowned historical significance of phenolic compounds found in plants as they are responsible for a countless variety of potential functional and physiological properties. In this regard, it is imperative to extract, identify, quantify, characterize and concentrate these target molecules to further apply them on formulations with biological properties (antioxidant, anti-inflammatory, immunomodulatory, etc.). In particular, phenolic compounds have been widely used as nutraceuticals. So, a detailed description of phenolic compounds extracted from plants, their synthesis pathways, and their mechanisms of action to further incorporate them into new nutraceuticals formulations and evaluate their efficacy to improve the quality of diet from a nutritional and medical point of view is necessary.

Nutraceuticals formulations have gained many attentions in the last years due to the growing awareness of the population about the importance of having healthy lifestyle habits and the key role of diet. They are considered as natural products derived from food used as medicinal or pharmaceutical formulations for their demonstrated physiological benefits; they can promote health and they include both, dietetic supplements and functional foods. Therefore, the short-term goal of nutraceuticals is to improve life quality and enhance the health status while their long-term goal is to increase lifespan while maintaining health.

In this Special Issue, articles (original research papers, future perspectives, hypotheses, opinions, reviews) will present the newest results of investigations and findings in the above-presented area  The aim of this Special Issue is to present recent results, recognize and explore new directions for future research in phenolic compounds obtained from vegetal sources. 

We invite researchers to contribute to this Special Issue. Submissions should be related to themes including but not restricted to:

• Structural characterization and modification of phenolic compounds.
• Scientific studies assessing the bioactive properties and health effects of phenolic compounds.
• Molecular action mechanisms behind the properties of phenolic compounds from plants.
• Innovative applications in the nutraceutical industry. 
• Toxicological evaluation of plant extract and phenolic compounds

Prof. Dr. Miguel A. Prieto Lage
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • phenolic compounds
  • action mechanisms
  • characterization
  • metabolic routes
  • synthesis pathways
  • nutraceuticals
  • plant diversity
  • health effects
  • extraction techniques
  • sustainable production

Published Papers

This special issue is now open for submission.
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