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Special Issue "Small Prokaryotic Proteins Interacting with Nucleic Acids"

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Biochemistry".

Deadline for manuscript submissions: 31 July 2021.

Special Issue Editors

Dr. Alicja Wegrzyn
Guest Editor
Institute of Biochemistry and Biophysics of the Polish Academy of Sciences, Gdansk, Poland
Interests: biology of bacteriophages; biodiversity of bacteriophages; regulation of bacteriophage development; regulation of phage gene expression; control of phage DNA replication; phage therapy; phages bearing genes of toxins; bacteriophage genomics
Special Issues and Collections in MDPI journals

Special Issue Information

Dear Colleagues,

There are many known proteins which specifically or non-specifically interacts with DNA or RNA. However, a special role is played by small proteins, present in prokaryotic cells, which interact with nucleic acids. Their functions were previously underestimated, but currently it appears that they play crucial roles in many processes occurring in prokaryotic cells, including gene expression regulation, DNA replication, genetic recombination and others. This special issue is devoted to publish papers focused on structures and functions of these proteins. Manuscripts on in vivo and in vitro studies are welcome, as are works presenting in silico analyses. Papers on genetic, biophysical and biochemical investigations will be considered. Both original papers and review articles can be submitted, provided they concern aspects of biological or biotechnological significance of small prokaryotic proteins interacting with DNA or RNA. It is expected that articles published in this special issue will significantly extend our understanding of regulation of molecular processes by these proteins.

Dr. Alicja Wegrzyn
Prof. Dr. Grzegorz Wegrzyn
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • Small proteins
  • protein-nucleic acids interactions
  • prokaryotic cells
  • gene expression regulation
  • DNA replication
  • DNA recombination
  • DNA repair
  • RNA metabolism

Published Papers

This special issue is now open for submission.
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