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Special Issue "Small Molecules, Influence of Molecular Pathways 2.0"

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Biology".

Deadline for manuscript submissions: 31 March 2022.

Special Issue Editor

Dr. Eng Shi Ong
E-Mail Website
Guest Editor
Department of Science, Singapore University of Technology and Design, Singapore 487372, Singapore
Interests: extraction technologies; separation techniques; metabonomics; molecular mechanism and signal transduction pathway
Special Issues and Collections in MDPI journals

Special Issue Information

Dear Colleagues,

Small organic molecules that have a molecular weight <1.5 kDa are generated or possibly modified by living cells and various biosystems. Techniques to identify small molecules have been successfully applied in a wide variety of fields, such as chemistry, engineering, medicine, and biology. In many areas, the hunt for small molecules has been extensively applied to study the intra- and extracellular metabolites present. In addition, they play major roles in metabolic pathways that may include energy metabolism, structural molecules, signaling, and others. It has been noted that these are dynamic molecules strongly influenced by genetics, diet, age, lifestyle, drugs, disease, and inflammation. As precision medicine progresses, small molecules that include lipids and others are being noted for their potential to act as unique biomarkers or other indicators.

The aim of this Special Issue is to present both original articles and review papers on the techniques and molecular mechanisms regulated or affected by small organic molecules. Studies on cell-based models, animal models, plant-based systems, and human studies are welcomed.

Dr. Eng Shi Ong
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • small molecules
  • molecular pathways
  • precision medicine
  • biomarkers

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Published Papers

This special issue is now open for submission.
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