Special Issue "Scavenger Receptors in Inflammation"
Deadline for manuscript submissions: closed (30 April 2021).
Interests: T cell activation; inhibitory receptors; scavenger receptors; inflammation; alternative splicing
Scavenger receptors are a diverse group of extracellular or membrane-bound receptors present in all metazoans, with individual members displaying varied roles in, cell differentiation, homeostasis, metabolism, apoptosis, and pathogen recognition, among many others. Given their broad interaction spectra, no unifying role has been ascribed to the ensemble of these receptors. However, many of them seem to participate in the control of the inflammatory response of the organism in response to injuries, infections, and other internal or external challenges. A major controversy arising from the recent advances in the field and published data is whether scavenger receptors promote inflammation or, on the contrary, their role is mostly anti-inflammatory. In this Special Issue, we will focus on the roles of different scavenger receptors of diverse genetic families in inflammation to finally clarify whether or not they share similar or related roles, or whether their functions may vary and be dependent on the biological context.
Dr. Alexandre M. Carmo
Dr. Liliana Oliveira
Manuscript Submission Information
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- scavenger receptors
- pattern recognition receptors
- pathogen clearance
- lipid transport
- chronic diseases
- immunological adaptive responses
- defense mechanisms
- immune homeostasis
- cytokine storms