Journal Browser

Journal Browser

Special Issue "Steroid Hormones and Sex Difference in Diseases"

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Biochemistry".

Deadline for manuscript submissions: 30 June 2021.

Special Issue Editor

Prof. Dr. Hong-Yo Kang
E-Mail Website
Guest Editor
1. Graduate Institute of Clinical Medical Sciences, College of Medicine, Chang Gung University, Taoyuan, Taiwan
2. Hormone Research Center, Chang Gung Memorial Hospital at Kaohsiung Medical Center 12F, No. 123, Ta-Pei Rd., Niao-Sung Dist., Kaohsiung City, Taiwan
Interests: sex difference; androgen receptor signaling; sex steroid hormones; endocrine disorders

Special Issue Information

Dear Colleagues,

Sex differences in the biology of different organ systems and the influence of sex hormones in modulating health and disease are increasingly relevant in clinical and research areas. Although major work has been focused on sex differences and sex hormones in reproductive systems, there is now increasing clinical evidence for sex differences in the incidence, morbidity, and mortality of cardiovascular, musculoskeletal, neuronal, liver, lung, and immune diseases. Studying the impact of sex differences is essential when they exist in the following aspects: anatomy; physiology; incidence and age of disease onset; symptoms impacting diagnosis of disease; disease severity, progression, and outcome; and response to treatment. Whether such differences are inherent and/or whether sex steroids play a role in modulating these differences is currently under investigation.

The purpose of this Special Issue is to collect original research and review articles on the latest findings to define sex differences under normal and specific disease states, with exploration of whether and how sex hormone signaling mechanisms may explain these clinical observations.

In this Special Issue, we welcome the submission of mini and full reviews, original research, short communications, as well as perspectives that cover but are not limited to the following topics:

  • Identification of inherent sex differences in anatomy and physiology;
  • Elucidating the importance of certain time points in life such as puberty, pregnancy, menopause, and aging;
  • Studying the expression and signaling of sex steroid receptors under normal vs. disease states;
  • Mechanisms of potential interplay between different sex steroids in diseases;
  • How sex steroids are beneficial or detrimental in diseases with sex difference;
  • Use of sex steroid signaling as biomarkers and therapeutic avenues in diseases with sex difference.

Prof. Dr. Hong-Yo Kang
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • Sex difference
  • Endocrine disorders
  • Gender difference
  • Androgen
  • Estrogen
  • Progesterone
  • Corticosteroids
  • Sex hormones
  • Sex steroids
  • Steroid hormones
  • Nuclear receptors
  • Hormone receptors

Published Papers

This special issue is now open for submission.
Back to TopTop