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Special Issue "Natural or Induced Thymic Senescence, Regenerative or Replacement Possibilities"

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Biochemistry".

Deadline for manuscript submissions: 31 July 2021.

Special Issue Editor

Dr. Krisztian Kvell
E-Mail Website
Guest Editor
Department of Pharmaceutical Biotechnology, Faculty of Pharmacy, University of Pecs, Pecs, Hungary
Interests: thymus; senescence; regeneration; physical activitiy; 3D tissue culture

Special Issue Information

Dear Colleagues,

The process of thymic senescence occurs in every human. Unfortunately, thymic senescence hampers the production of naive T cells attributed with elevated chances of infection, cancer and autoimmune disorders. Some stimuli accelerate thymic senescence including chemicals, hormones and infections. Other factors may decelerate thymus aging including perturbations of the hormonal system, genetic mutations or chemical compounds. Thymic senescence research sheds light on underlying molecular events to pinpoint therapeutic targets of intervention. Alternatively, regenerative and replacement approaches may postpone thymus senescence and enhance T cell production. This in turn could decrease the incidence of infections, cancer and autoimmune diseases. The forecasted gain in healthcare costs and quality of life have significant economic and social interest.

We invite researchers of multiple fields to present their results and propose prospective applications by contributing original research articles or review papers in the topic of thymus senescence and regeneration. Manuscripts may deal with the findings obtained on patients, animal models as well as on cells and tissues.

Dr. Krisztian Kvell
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • immunity
  • thymus
  • senescence
  • progeria
  • regeneration

Published Papers

This special issue is now open for submission.
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