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Special Issue "Toxicity and Metabolism of Trace Element"

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Toxicology".

Deadline for manuscript submissions: 31 October 2021.

Special Issue Editor

Dr. Ujang Tinggi
E-Mail Website
Guest Editor
Queensland Health Forensic and Scientific Services, 39 Kessels Road, Coopers Plains, QLD 4108, Australia
Interests: bioavailability; heavy metals; trace elements; elemental analysis; toxicity; metabolism
Special Issues and Collections in MDPI journals

Special Issue Information

Dear Colleagues,

Advancing global industrialization has led to a rapid rise in the demand and use of mineral elements, including trace and rare earth elements and their nanoparticles. This use of mineral elements has resulted in increased exposure in humans, and the impact on the environment from chemical contaminants. Health concerns from high trace element exposure ranging from various neurological dysfunctions to impaired body growth and deformity are well documented. The toxic effects of trace elements not only exert their toxicity at certain concentrations but also in their chemical species (oxidation states) and in critical metal mixtures. Trace element deficiencies such as anemia (iron) and goiter (iodine) in some populations are also a concern. As emerging diseases associated with chronic exposure and deficiency of trace elements have become more apparent, interest has increased in investigating the role of gene expressions in metal-binding proteins as a means to identify biomarkers for early detection of diseases and to understand the pathological mechanisms. However, further understanding is needed of the toxicity mechanisms and mechanistic actions on cause and effect in relation to metabolism and regulation of trace elements on specific target cells and tissues. This research area is still a significant challenge.

Dr. Ujang Tinggi
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • trace element
  • mineral elements
  • exposure
  • toxicity
  • metabolism

Published Papers

This special issue is now open for submission.
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