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Special Issue "Molecular Genetics and Biological Mechanism of Upper Gastrointestinal Diseases 2.0"

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Biology".

Deadline for manuscript submissions: 30 April 2022.

Special Issue Editors

Prof. Dr. Ines Gockel
E-Mail Website
Guest Editor
Department of Visceral, Transplant, Thoracic and Vascular Surgery, University Hospital of Leipzig, Leipzig, Germany
Interests: moleculargenetic analyses of upper gastrointestinal diseases;esophageal and gastric cancer; intraoperative imaging (hyperspectral imaging and ICG); robotics;minimally invasive visceral surgery
Special Issues, Collections and Topics in MDPI journals
Dr. Johannes Schumacher
E-Mail Website
Guest Editor
Institute of Human Genetics, University Hospital of Marburg, Marburg, Germany
Interests: schizophrenia; bipolar disorder; genome-wide association study
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Moleculargenetic decryptions of upper gastrointestinal disorders have evolved into an emerging field with increasing attention. This holds for benign and malignant diseases and extends far beyond prediction and prevention. Extensive and holistic analyses of the moleculargenetic background in multifactorial upper gastrointestinal diseases—including genetic germline risk variants and somatic mutations, as well as corresponding functional consequences—although still developing and in progress, have already led to a relevant rise in our current understanding. This new knowledge has the ability of early prediction and the possibility of developing targeted therapies, as well as the identification of genetic profiles to predict drug resistance.

In this Special Issue of IJMS, we are presenting the state-of-the-art of the moleculargenetic and biological aspects of upper gastrointestinal diseases by internationally prominent and renowned authors.

Prof. Dr. Ines Gockel
Dr. Johannes Schumacher
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • molecular genetic analyses of upper gastrointestinal diseases
  • esophageal cancer
  • squamous cell carcinoma of the esophagus
  • Barrett’s adenocarcinoma
  • achalasia
  • GERD (gastroesophageal reflux disease)
  • gastric cancer
  • molecular subtypes of esophageal and gastric cancer
  • multifactorial upper gastrointestinal diseases
  • somatic mutations

Related Special Issue

Published Papers

This special issue is now open for submission.
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