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International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic. The journal’s Editor-in-Chief and/or designated EBM will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Coordination Compounds as Diagnostic, Therapeutic and Theranostic Agents
edited by and
submission deadline 30 Apr 2024 | 1 articles | Viewed by 1414 | Submission Open
Keywords: coordination compounds; luminescence; anticancer agents; antibacterial agents
(This special issue belongs to the Section Molecular Pharmacology)
Liquid Biopsy in the Approach of Non-communicable Chronic Diseases (NCCD) and Cancer
edited by Fernando Luiz Affonso Fonseca
submission deadline 30 Apr 2024 | 1 articles | Viewed by 1398 | Submission Open
Keywords: biomarkers; alternative biological matrices; laboratory nethods; precision medicine; liquid biopsy; cancer; non-communicable chronic diseases; clinical studies; preclinical studies
(This special issue belongs to the Section Molecular Oncology)
The Function of Mitochondrial Metabolism in Heart and Skeletal Muscle
edited by Yoshitake Cho
submission deadline 30 Apr 2024 | 1 articles | Viewed by 1382 | Submission Open
Keywords: heart; skeletal muscle; metabolism; glucose; mitochondria; metabolic disorder
(This special issue belongs to the Section Molecular Endocrinology and Metabolism)
Mitochondrial Dysfunction in Autoimmune Diseases submission deadline 30 Apr 2024 | 1 articles | Viewed by 1377 | Submission Open
Keywords: autoimmune diseases; autoantibodies; autophagy; mitophagy; mitochondrial hyperpolarization; mitochondrial dysfunction; oxidative phosphorylation; oxidative damage; fatigue; chronic inflammation
(This special issue belongs to the Section Molecular Immunology)
Plant Secondary Metabolites in Plant Defence against Abiotic and Biotic Stresses 3.0
edited by
submission deadline 30 Apr 2024 | 2 articles | Viewed by 1352 | Submission Open
Keywords: abiotic and biotic stress; sustainable plant defense; volatile organic compounds (VOCs); antioxidants; priming; signaling; tolerance/resistance
(This special issue belongs to the Section Molecular Plant Sciences)
Roles of Extracellular Vesicles in Cerebrovascular Diseases
edited by Jinju Wang
submission deadline 30 Apr 2024 | 1 articles | Viewed by 1346 | Submission Open
Keywords: exosomes; cerebrovascular disease; stroke; hypertension-related dementia; aging-related dementia
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
RNA Function and Structure
edited by Anna Wacker
submission deadline 30 Apr 2024 | 1 articles | Viewed by 1345 | Submission Open
Keywords: RNA architecture; molecular motions; structural dynamics; NMR spectroscopy; RNA– RNA interaction; RNA-binding proteins; RNA– ligand complex; RNA recognition; RNA modifications; RNA targeting
(This special issue belongs to the Section Molecular Biology)
Antimicrobial and Cytotoxic Properties of Silver Nanoparticles submission deadline 30 Apr 2024 | 1 articles | Viewed by 1311 | Submission Open
Keywords: silver nanoparticles; antimicrobial activity; silver nanoparticles citotoxicity; silver nanoparticles genotoxicity; anti-cancer silver; green synthesis; alternative antimicrobials; silver environmental effects
(This special issue belongs to the Section Molecular Microbiology)
Nanoparticle-Based Drug Targeting
edited by
submission deadline 30 Apr 2024 | 1 articles | Viewed by 1289 | Submission Open
Keywords: nanoparticles; drug targeting; stimuli-sensitive drug delivery; controlled release of bioactive molecules; theranostic application; nano-vaccine
(This special issue belongs to the Section Materials Science)
Valuable Bioactive Compounds from Prokaryotic and Eukaryotic Organisms
edited by Blaženka Kos, and
submission deadline 30 Apr 2024 | 1 articles | Viewed by 1287 | Submission Open
Keywords: bioactive compounds; prokaryotic and eukaryotic organisms; specific metabolites; biological and chemical potential of prokaryotic and eukaryotic organisms
(This special issue belongs to the Section Biochemistry)
Advancements in Biocompatible Materials for Dental Applications submission deadline 30 Apr 2024 | 1 articles | Viewed by 1239 | Submission Open
Keywords: bioactivity; biocompatibility; endodontic treatment; restorative material; esthetic procedure; microsurgical steps; prosthetic— direct and indirect restorations; digital and printing procedures
(This special issue belongs to the Section Materials Science)
Selected Papers from the International Conference on Plant Systems Biology submission deadline 30 Apr 2024 | 1 articles | Viewed by 1235 | Submission Open
Keywords: abiotic and oxidative stress; bioinformatics and computational modeling; genetics and genomics; molecular breeding; plant biotechnology; molecular biology; plant systems biology
(This special issue belongs to the Section Molecular Plant Sciences)
Molecular Linkage between Atherosclerosis and Extracellular Vesicles
edited by Wioletta Olejarz
submission deadline 30 Apr 2024 | 1 articles | Viewed by 1227 | Submission Open
Keywords: atherosclerosis; extracellular vesicles; exosomes; vascular inflammation; stroke; biomarkers; miRNA; stem and progenitor cells; cardiovascular diseases
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Prostate Cancer: Novel Research and Innovative Therapeutic Strategies submission deadline 30 Apr 2024 | 2 articles | Viewed by 1222 | Submission Open
Keywords: prostate cancer; therapeutic strategy; castration-resistant PCa
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Oxidative Stress and Mitochondrial Dysfunction
edited by
submission deadline 30 Apr 2024 | 1 articles | Viewed by 1204 | Submission Open
Keywords: oxidative/nitrosative stress; mitochondrial dysfunction; gene and protein expressions; neuroinflammation; stroke; traumatic brain injury; Alzheimer’ s disease; Parkinson’ s disease; amyotrophic lateral sclerosis; multiple sclerosis; acute and chronic neurodegenerations
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Adipokines as Peripheral Signals for the Integration of Energy Balance and Reproduction submission deadline 30 Apr 2024 | 1 articles | Viewed by 1202 | Submission Open
Keywords: adipokines; obesity; fertility; reproduction; hypothalamic– pituitary– gonadal axis
(This special issue belongs to the Section Biochemistry)
Molecular Advances in Dental Pulp Tissue Engineering 2.0 submission deadline 30 Apr 2024 | 1 articles | Viewed by 1197 | Submission Open
Keywords: tissue engineering and regenerative medicine (TERM); pulp regeneration; scaffold materials; stem cells; bioactive molecules; dentin matrix proteins
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Antimicrobial Peptides, Cytokines, Chemokines and Danger Molecules in Immunity and Autoimmunity
edited by
submission deadline 30 Apr 2024 | 2 articles | Viewed by 1195 | Submission Open
Keywords: antimicrobial peptides; antimicrobial chemokines; immune cells; immune responses; autoimmunity
(This special issue belongs to the Section Molecular Immunology)
Mitochondrial Dysfunction in Aging and Diseases Affecting the Neuromuscular System
edited by
submission deadline 30 Apr 2024 | 1 articles | Viewed by 1174 | Submission Open
Keywords: mitochondrial physiology; mitochondria in ALS; mitochondria in SMA; mitochondria in neuroinflammation; mitochondria in muscular dystrophy; mitochondria in sarcopenia; mitochondria in myasthenia gravis; mitochondria in muscle physiology; mitochondria and motoneurons; mitochondria and therapy
(This special issue belongs to the Section Biochemistry)
Molecular Advances in Bone Metabolism and Disorders
edited by
submission deadline 30 Apr 2024 | 1 articles | Viewed by 1162 | Submission Open
Keywords: bone metabolism; molecular mechanisms; molecular biology of bone remodeling; bone aging; bone disease; osteoporosis; drug development; osteoclast; osteoblast; osteocyte
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Artificial Intelligence/ML in Molecular Cancer Research
edited by
submission deadline 30 Apr 2024 | 1 articles | Viewed by 1152 | Submission Open
Keywords: artificial intelligence; machine learning; deep learning; cancer; multi-omics analysis; statistical methods
(This special issue belongs to the Section Molecular Informatics)
Neuropeptides and Neurological Diseases
edited by
submission deadline 30 Apr 2024 | 1 articles | Viewed by 1148 | Submission Open
Keywords: somatostatin receptors; ghrelin receptors; cortistatin; neuroendocrine and immune systems; neurodegeneration; cardiovascular; tumors; intracellular signaling
(This special issue belongs to the Section Molecular Neurobiology)
Interactions between the Environment and the Intestinal Epithelium: Gut Barrier Function and Inflammation submission deadline 30 Apr 2024 | 1 articles | Viewed by 1142 | Submission Open
Keywords: advances on the environmental factors including nano- and micro-particles and pesticides; food additives; microbiota metabolites with anti- or pro-inflammatory properties; intestinal permeability; intestinal stem cells
(This special issue belongs to the Section Molecular Immunology)
Inflammatory Responses and Immunity under Stress
edited by Judith-Irina Buchheim
submission deadline 30 Apr 2024 | 1 articles | Viewed by 1071 | Submission Open
Keywords: psychoneuroimmunology; immunity; stress-modulated immune response; autoimmunity; hypersensitivity; stressors; environmental stress; allostatic load; autonomic nervous system (ANS); hypothalamic– pituitary– adrenal (HPA) axis
(This special issue belongs to the Section Molecular Immunology)
Editorial Board Members’ Collection Series: “Molecular Dynamics” submission deadline 30 Apr 2024 | 1 articles | Viewed by 1063 | Submission Open
Keywords: quantum mechanics; classical mechanics; hybrid QM/MM; molecular dynamics at the atomic level; steered molecular dynamics; coarse-graining; docking(protein– protein; protein– ligand); the molecular dynamics of protein– ligand interactions; drug design; virtual screening
(This special issue belongs to the Section Molecular Biophysics)
Molecular Immunity and Defense: Oral and Periodontal Health
edited by
submission deadline 30 Apr 2024 | 1 articles | Viewed by 1047 | Submission Open
Keywords: periodontal pathology; implant mucositis; peri impalntitis; root fracture; endodontic lesion
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Cellular Stress and Genomics in Eukaryotes
edited by
submission deadline 30 Apr 2024 | 1 articles | Viewed by 1025 | Submission Open
Keywords: genomic instability; chromosomal instability; premature mitoses; premature chromosome condensation; cell death; replication stress; DNA damage; cell cycle checkpoints; synthetic lethality; chromothripsis; eukaryotic cells
(This special issue belongs to the Section Molecular Biology)
Molecular Genetics of Human Diseases: Focus on Intestinal Cancers
edited by
submission deadline 30 Apr 2024 | 1 articles | Viewed by 980 | Submission Open
Keywords: intestinal cancer; dietary compound; nutrigenomics; DNA methylation; non-coding RNAs; histone modifications; epigenetic changes; gut microbiome; intestinal disease; environmental factors
(This special issue belongs to the Section Molecular Genetics and Genomics)
Molecular Mechanism in Neurodegeneration
edited by Milena Atanasova and
submission deadline 30 Apr 2024 | 1 articles | Viewed by 970 | Submission Open
Keywords: abnormal protein dynamics with misfolding; defective degradation; proteasomal dysfunction and aggregation; often with actions and mutations of molecular chaperones; oxidative stress (OS) and formation of free radicals/reactive oxygen species (ROS)
(This special issue belongs to the Section Molecular Neurobiology)
The Plasticity of the Innervation of the Urogenital System
edited by
submission deadline 30 Apr 2024 | 1 articles | Viewed by 955 | Submission Open
Keywords: neuronal plasticity; urogenital tract; innervation; nerve growth factors; neuropeptides; neurotrophins; nerve injury; nerve regeneration; pelvic nerves; autonomic nervous system; smooth muscle dysfunction; bladder hyperactivity; erectile dysfunction; vaginal atrophy; neuromodulation
(This special issue belongs to the Section Molecular Neurobiology)
New Insights into Proteomics and Applications in Molecular Diagnostics and Systems Biology
edited by
submission deadline 30 Apr 2024 | 1 articles | Viewed by 940 | Submission Open
Keywords: mass spectrometry; liquid chromatography; tandem mass spectrometry (MS/MS); quantitative proteomics; shotgun proteomics; label-free quantification; post-translational modifications; protein– protein interactions; proteogenomics; single-cell proteomics; data analysis; bioinformatics; functional proteomics; phosphoproteomics; glycoproteomics; biomarker discovery; top– down proteomics; clinical applications; disease proteomics; systems biology
(This special issue belongs to the Section Molecular Informatics)
Insights into the Mechanisms and Driving Forces of Biomolecular Adsorption Processes
edited by Ana Cristina Dias-Cabral and Paula Fraga-García
submission deadline 30 Apr 2024 | 1 articles | Viewed by 913 | Submission Open
Keywords: biomolecule adsorption; biomolecule separation; interaction mechanisms; driving forces; biophysical studies; interaction thermodynamics; downstream processing; materials and surface science; interfacial chemistry
(This special issue belongs to the Section Molecular Biophysics)
Molecular Advances and Insights into Brain Hypoxia
edited by Natalia N. Nalivaeva
submission deadline 30 Apr 2024 | 1 articles | Viewed by 908 | Submission Open
Keywords: hypoxia; ischemia; HIF-1; COVID-19; hypoxic pre- and postconditioning; gene expression; cell death; brain tolerance; neurodegeneraion; neuroprotection
(This special issue belongs to the Section Molecular Neurobiology)
Research Progress of Tumor Endothelial Cells
edited by
submission deadline 30 Apr 2024 | 1 articles | Viewed by 898 | Submission Open
Keywords: tumorigenesis; cancer; metastasis; endothelial cells (ECs); tumor cells; tumor microenvironment; metabolism; proliferation; invasion; vascular; microvascular; tumor angiogenesis; sprouting
(This special issue belongs to the Section Molecular Oncology)
Epigenetic Dysregulation in Cancers: From Mechanism to Therapy
edited by Saverio Candido
submission deadline 30 Apr 2024 | 1 articles | Viewed by 890 | Submission Open
Keywords: epigenetics; non-coding RNAs; microRNAs; histone modifications; chromatin remodeling; DNA methylation; 5-methyl-cytosine; biomarkers; cancer; promoter and body methylation
(This special issue belongs to the Section Molecular Oncology)
Molecular and Cellular Mechanisms Underlying Gastrointestinal Diseases
edited by
submission deadline 30 Apr 2024 | 1 articles | Viewed by 855 | Submission Open
Keywords: gastrointestinal diseases; liver; pancreas; inflammation bowel diseases; dyspepsia
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Mitochondrial Footprint in Neurological Pathology submission deadline 30 Apr 2024 | 1 articles | Viewed by 828 | Submission Open
Keywords: neurological disorders; mitochondrial bioenergetics; mitochondrial dynamics; immunometabolism; biomarkers; mitochondrial medicine
(This special issue belongs to the Section Molecular Neurobiology)
Animal Experimental Models in Bone Metabolic Disease 2.0
edited by Jose Luis Pérez-Castrillón and
submission deadline 30 Apr 2024 | 1 articles | Viewed by 826 | Submission Open
Keywords: animal experimental models; therapeutic targets; pathophysiology; bone metabolic disease
(This special issue belongs to the Section Molecular Endocrinology and Metabolism)
Bioactive Compounds for the Prevention and Treatment of Human Diseases
edited by Marek Gogacz
submission deadline 30 Apr 2024 | 1 articles | Viewed by 824 | Submission Open
Keywords: bioactive compounds; antioxidant activity; inflammation; natural plants and products; macro and microelements; vitamins; immune system; health benefits; anticancer activity; disease prevention
(This special issue belongs to the Section Bioactives and Nutraceuticals)
Editorial Board Members’ Collection Series: “Neuroinflammation” submission deadline 30 Apr 2024 | Viewed by 819 | Submission Open
Keywords: neuroinflammation; amyotrophic lateral sclerosis; multiple sclerosis; Parkinson's disease; Alzheimer's disease; ataxias; traumatic brain injury; spinal cord injury
(This special issue belongs to the Section Molecular Immunology)
Molecular Advances in Circadian Rhythm and Metabolism
edited by Olga Cela and Rosella Scrima
submission deadline 30 Apr 2024 | 1 articles | Viewed by 765 | Submission Open
Keywords: circadian rhythms; metabolism; clock genes; protein processing/post-translational modifications; chronomedicine
(This special issue belongs to the Section Molecular Endocrinology and Metabolism)
Advances in Molecular Studies of Mercury Toxicity
edited by
submission deadline 30 Apr 2024 | 1 articles | Viewed by 757 | Submission Open
Keywords: mercury; methylmercury; toxicity; cells; tissues; signaling molecules; molecular determinants; genetic susceptibility; developmental susceptibility
(This special issue belongs to the Section Molecular Toxicology)
The Lysosome in Human Health and Diseases submission deadline 30 Apr 2024 | 1 articles | Viewed by 747 | Submission Open
Keywords: lysosomal storage disorders; lysosomal hub; lysosomal signalling; lysosomal trafficking; nutrient sensing; cell death; disease models; biomarkers; RNA-therapeutics
(This special issue belongs to the Section Molecular Biology)
Endometriosis and Endometriosis-Associated Cancer: Molecular Pathologies, Diagnosis and Therapeutic Strategies
edited by Uri Dior and Tamar Perri
submission deadline 30 Apr 2024 | 1 articles | Viewed by 709 | Submission Open
Keywords: endometriosis; ovarian cancer; breast cancer; epigenetics; gene expression
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Molecular Interactions between Plants and Pests
edited by
submission deadline 30 Apr 2024 | 1 articles | Viewed by 700 | Submission Open
Keywords: immunity molecular mechanisms; plant immunity; plant pests; root microbiome; plant defense signaling; defense metabolites; plant defense tolerance; plant receptors; effectors; elicitors; phytophagous arthropod co-evolution; effectors
(This special issue belongs to the Section Molecular Plant Sciences)
Thermophilic, Heterotrophic Anaerobes—Recent Advances in Phylogeny and Biotechnology
edited by
submission deadline 30 Apr 2024 | 1 articles | Viewed by 653 | Submission Open
Keywords: thermophilic; anaerobe; genetic engineering; biofuels; fine chemicals; enzymes
(This special issue belongs to the Section Molecular Microbiology)
Computational Simulation of Macromolecular Processes Involved in Disease submission deadline 30 Apr 2024 | 1 articles | Viewed by 650 | Submission Open
Keywords: computational biology; virtual modeling; drug discovery; molecular dynamics; molecular mechanism of disease
(This special issue belongs to the Section Molecular Biophysics)
Recent Advances in Organic Chemistry: Molecules Synthesis and Reactions submission deadline 30 Apr 2024 | 1 articles | Viewed by 646 | Submission Open
Keywords: bioactive natural products; organocatalysis; photoredox reactions; free-radical reactions; organometallic reactions; organic synthesis
(This special issue belongs to the Section Physical Chemistry and Chemical Physics)
Molecular Mechanism Underlying Memory Modulated by Emotions and Stress
edited by
submission deadline 30 Apr 2024 | Viewed by 621 | Submission Open
Keywords: emotions; stress; memory; pathology
(This special issue belongs to the Section Molecular Neurobiology)
Recent Molecular Research in Interaction of Plants and Fungi
edited by
submission deadline 30 Apr 2024 | 1 articles | Viewed by 585 | Submission Open
Keywords: plant-fungi interactions; soil microorganisms; ecosystem processes; crop yield; bioactive compounds; bioremediation; mutualistic relationships; carbon cycle; climate change
(This special issue belongs to the Section Molecular Microbiology)
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