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Insects
Special Issues
Molecular Basis of Adaptation in Arthropods
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Molecular Basis of Adaptation in Arthropods

A special issue of Insects (ISSN 2075-4450). This special issue belongs to the section "Insect Molecular Biology and Genomics".

Deadline for manuscript submissions: closed (30 September 2021) | Viewed by 2227

Special Issue Editors

Dr. Nicky Wybouw

E-Mail Website
Guest Editor
Department of Biology, Ghent University, 9000 Ghent, Belgium
Interests: herbivory; detoxification; symbiosis; endosymbionts; pesticide resistance; genomics
Dr. Wannes Dermauw

E-Mail Website
Guest Editor
Department of Plants and Crops, Faculty of Bioscience Engineering, Ghent University, 9000 Ghent, Belgium
Interests: arthropod genomics; pesticide resistance; plant-herbivore interactions; molecular acarology

Special Issue Information

Arthropods originated more than 500 MYA and have expanded into all major habitats. They have evolved herbivorous, detritivorous, parasitic and carnivorous lifestyles, and exhibit a remarkable ability to adapt to (novel) nutritional challenges, resulting in highly dynamic feeding ecologies. Arthropod populations also quickly adapt to several anthropogenic stressors, such as pesticides, heavy metals and changing climate conditions. In this Special Issue, we welcome all studies that aim to unravel the molecular basis of these adaptation processes and specifically encourage studies implementing whole-genome-based approaches and/or reverse genetics tools (e.g. CRISPR-Cas9 and RNAi), to address their research hypotheses.

Dr. Nicky Wybouw
Dr. Wannes Dermauw
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Insects is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • molecular mechanisms
  • adaptation
  • xenobiotics
  • nutritional physiology
  • environmental stress
  • genomics

Published Papers (1 paper)

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Research

15 pages, 2075 KiB  
Article
Identification of Wild-Type CYP321A2 and Comparison of Allelochemical-Induced Expression Profiles of CYP321A2 with Its Paralog CYP321A1 in Helicoverpa zea
by Shengyun Li, Song Chen, Xingcheng Xie, Shuanglin Dong and Xianchun Li
Insects 2021, 12(1), 75; https://0-doi-org.brum.beds.ac.uk/10.3390/insects12010075 - 15 Jan 2021
Cited by 3 | Viewed by 1695
Abstract
One possible way to overcome the diversity of toxic plant allelochemicals idiosyncratically distributed among potential host plants is to have more counterdefense genes via gene duplication or fewer gene losses. Cytochrome P450 is the most important gene family responsible for detoxification of the [...] Read more.
One possible way to overcome the diversity of toxic plant allelochemicals idiosyncratically distributed among potential host plants is to have more counterdefense genes via gene duplication or fewer gene losses. Cytochrome P450 is the most important gene family responsible for detoxification of the diversity of plant allelochemicals. We have recently reported the identification and cloning of the transposon (HzSINE1)-disrupted non-functional CYP321A2, a duplicated paralog of the xenobiotic-metabolizing P450 CYP321A1 from a laboratory colony of Helicoverpa zea. Here we report the identification of the wild-type intact allele of CYP321A2 from another H. zea colony. This CYP321A2 allele encodes a deduced protein of 498 amino acids and has the P450 signature motifs. Quantitative RT-PCR experiments showed that this CYP321A2 allele was highly expressed in midgut and fat body and achieved the highest expression level in the developmental stage of 5th and 3rd instar larvae. CYP321A2 and CYP321A1 were constitutively expressed in low levels but can be differentially and significantly induced by a range of the plant allelochemicals and plant signal molecules, among which xanthotoxin, flavone, and coumarin were the most prominent inducers of CYP321A2 both in midgut and fat body, whereas flavone, coumarin, and indole-3-carbinol were the prominent inducers of CYP321A1 in midgut and fat body. Moreover, xanthotoxin- and flavone-responsive regulatory elements of CYP321A1 were also detected in the promoter region of CYP321A2. Our results enrich the P450 inventory by identifying an allelochemical broadly induced CYP321A2, a paralog of CYP321A1 in H. zea. Our data also suggest that the CYP321A2/CYP321A1 paralogs are a pair of duplicated genes of multigene families and CYP321A2 could potentially be involved in the detoxification of plant allelochemicals and adaptation of H. zea to its chemical environment. Full article
(This article belongs to the Special Issue Molecular Basis of Adaptation in Arthropods)
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