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Recent Clinical Advances in Vitreoretinal Surgery

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A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Ophthalmology".

Deadline for manuscript submissions: closed (20 January 2023) | Viewed by 6905

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Special Issue Editors

Dr. Pasquale Loiudice

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Guest Editor

Ophthalmology, Department of Surgical, Medical, Molecular Pathology and of Critical Area, University of Pisa, Pisa, Italy
Interests: retina; surgical retina; retinal detachment; epiretinal membrane; macular hole; proliferative vitreoretinopathy
Special Issues, Collections and Topics in MDPI journals

Prof. Dr. Michele Figus

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Guest Editor

Department of Surgical, Medical and Molecular Pathology and Critical Care Medicine, University of Pisa, 56124 Pisa, Pisa, Italy
Interests: glaucoma; ocular surface; anterior segment surgery; uveitis
Special Issues, Collections and Topics in MDPI journals

Prof. Dr. Marco Mura

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Guest Editor

1. Department of Translational Medicine, University of Ferrara, Ferrara, Italy
2. King Khaled Eye Specialist Hospital, Riyadh, Saudi Arabia
3. Department of Ophthalmology, University of Illinois, Chicago, USA
Interests: retina; surgical retina; retinal detachment; epiretinal membrane; macular hole; proliferative vitreoretinopathy

Special Issue Information

Dear Colleagues,

Recent advances in the techniques and technology of vitreoretinal surgery have allowed significant progress. Retinal surgeons are required to face challenging cases and to improve the rate of success of their work. Cutting edge research has developed in several fields of application. Some of these improvements include the introduction of intraoperative optical coherence tomography for real-time retinal images; the employment of a 3D vision system; the development of new ocular dyes and tamponade; and the use of new tools, machines, techniques, and biological derivates. Progress in understanding the physiopathology of many retinal conditions can guide the treatment algorithm.

This Special Issue of Journal of Clinical Medicine aims to collect contributions focused on advances in vitreoretinal surgery, including development research, and their clinical use inexperimental and clinical content.

Dr. Pasquale Loiudice
Prof. Dr. Michele Figus
Prof. Dr. Marco Mura
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

digitally assisted retinal surgery
intraoperative optical coherence tomography
macular peeling
ocular dye
ocular tamponade
retina
retinal surgery
surgical technique surgical tool
vitrectomy

Published Papers (4 papers)

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Research

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13 pages, 319 KiB

Open AccessArticle

Visual Outcomes and Prognostic Factors of Traumatic Endophthalmitis Treated by Pars Plana Vitrectomy: 11 Years Retrospective Analysis

by Mădălina-Claudia Hapca, Ștefan Cristian Vesa and Simona-Delia Nicoară

J. Clin. Med. 2023, 12(2), 502; https://0-doi-org.brum.beds.ac.uk/10.3390/jcm12020502 - 07 Jan 2023

Cited by 3 | Viewed by 1161

Abstract

Aim: To evaluate the visual outcome of traumatic endophthalmitis and describe the risk factors associated with poor visual acuity and retinal detachment (RD) development over an 11-year period. Methods: Medical records of 34 patients with traumatic endophthalmitis who underwent PPV over a period of 11 years (1 January 2010–31 December 2020) were reviewed. We extracted details regarding demographic data, initial and final best corrected visual acuity (BCVA) using a standard Snellen chart, wound and IOFB characteristics, ocular associated lesions, and treatment. The outcome was evaluated according to the final BCVA which was defined as poor < 0.1 or good ≥ 0.1 Results: Endophthalmitis rate was 29.8% in open globe injuries. The mean age was 43.6 ± 16.5 years and the majority of patients were males (32 out of 34, 94.1%). All patients received systemic (moxifloxacin) and intravitreal antibiotherapy. We performed pars plana vitrectomy (PPV) in all cases. Poor visual outcome was associated with wound size ≥ 3 mm (p = 0.02), the association of IOFB (p = 0.016), and the development of RD (p = 0.00). The presence of IOFB (p = 0.01) and wound size ≥ 3 mm (p = 0.01) were statistically associated with RD development. After treatment, 47.05% of patients achieved final BCVA ≥ 0.1. Conclusion: Wound size ≥ 3 mm, IOFB and RD were risk factors for poor visual outcomes in traumatic endophthalmitis. Full article

(This article belongs to the Special Issue Recent Clinical Advances in Vitreoretinal Surgery)

10 pages, 1274 KiB

Open AccessArticle

Intraocular Temperature Distribution in Eyes Undergoing Different Types of Surgical Procedures during Vitreous Surgery

by Kei Shinoda, Soiti C. Matsumoto, Kazuma Yagura, Gaku Terauchi, Takuhei Shoji, Yuji Yoshikawa, Yuro Igawa, Atsushi Mizota and Yozo Miyake

J. Clin. Med. 2022, 11(7), 2053; https://0-doi-org.brum.beds.ac.uk/10.3390/jcm11072053 - 06 Apr 2022

Cited by 4 | Viewed by 1407

Abstract

Vitreous temperature has been reported to vary during intraocular surgery. We measured the temperature at three intraocular sites, just posterior to the crystalline lens (BL), mid-vitreous (MV), and just anterior to the optic disc (OD), and investigated temperature changes before and after different types of surgical procedures in 78 eyes. The mean temperature at the beginning was 30.1 ± 1.70 °C in the anterior chamber, 32.4 ± 1.41 °C at the BL, 33.8 ± 0.95 °C at the MV, and 34.7 ± 0.95 °C at the OD. It was lowest at the BL, and highest at the OD. The mean temperature after cataract surgery was slightly lower especially at an anterior location. Thus, the temperature gradient became slightly flatter. The mean temperature after core vitrectomy was even lower at all sites and a gradient of the temperature was not present. The mean temperature after membrane peeling was significantly higher than that after core vitrectomy, and there was no gradient. The mean temperature after fluid/air exchange was lower at the BL and higher at the MV and at the OD. Thus, a gradient of higher temperatures at the OD appeared. The intraocular temperature distribution is different depending on the surgical procedure which can then change the temperature gradient. The temperature changes at the different intraocular sites and the gradients should be further investigated because they may affect the physiology of the retina and the recovery process. Full article

(This article belongs to the Special Issue Recent Clinical Advances in Vitreoretinal Surgery)

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11 pages, 8189 KiB

Open AccessArticle

Long-Term Outcome of Corneal and Anterior Chamber Angle Parameters after Combined Laser Iridotomy and Iridoplasty Using Dual Scheimpflug Analyzer: 1 Year Results

by Hyun-kyung Cho and Wooseok Choae

J. Clin. Med. 2022, 11(3), 813; https://0-doi-org.brum.beds.ac.uk/10.3390/jcm11030813 - 03 Feb 2022

Cited by 2 | Viewed by 1531

Abstract

Background: To investigate the outcomes of corneal and anterior chamber angle (ACA) parameters after laser iridotomy (LI) combined with peripheral iridoplasty (PI) using dual Scheimpflug analyzer in the long term. Methods: Fifty-eight eyes (58 subjects) with shallow AC were included in this prospective cohort study. Images of the Dual Scheimpflug analyzer were obtained before, 1 week, and 1 year after LI and PI. Pachymetry from three zones (central, middle, and peripheral), corneal aberration, and spherical equivalent (SE) were acquired. AC depth (ACD), AC volume (ACV), ACA from four quadrants, and intraocular pressure (IOP) were also obtained. For comparison of the results, the linear mixed-effects model was employed. Results: ACD significantly increased from 2.09 ± 0.25 mm to 2.10 ± 0.23 mm at 1 year after laser (all p < 0.05). ACV and ACA increased significantly after laser at 1 year (all p < 0.05). IOP significantly decreased from 15.97 ± 4.20 mmHg to 13.73 ± 2.63 mmHg at 1 year (all p < 0.0001). No significant changes were found in the coma, trefoil, total corneal aberration, pachymetry from three zones, corneal volume, central corneal thickness, and SE after LI and PI until 1 year (all p > 0.05). Conclusions: LI plus PI ameliorated parameters of ACA efficiently and significantly reduced IOP in eyes with shallow AC until 1 year of long-term follow-up. However, parameters of the cornea and SE were not influenced by LI with PI until after 1 year. Full article

(This article belongs to the Special Issue Recent Clinical Advances in Vitreoretinal Surgery)

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Review

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27 pages, 790 KiB

Open AccessReview

The Role of Silicone Oil in the Surgical Management of Endophthalmitis: A Systematic Review

by Fabrizio Sinisi, Marco Della Santina, Pasquale Loiudice, Michele Figus and Giamberto Casini

J. Clin. Med. 2022, 11(18), 5445; https://0-doi-org.brum.beds.ac.uk/10.3390/jcm11185445 - 16 Sep 2022

Cited by 6 | Viewed by 2229

Abstract

(1) Background: We aimed to systematically review the current literature to evaluate if in patients with postoperative endophthalmitis treated with pars plana vitrectomy, silicone oil tamponade could provide a useful contribution to the control and eradication of infection and if it could influence anatomical recovery and functional outcome. (2) Randomized controlled trials, cross-sectional studies, case series, and case reports published in the English language in peer-reviewed journals were included. No restriction was placed based on the study location. We used medical subject headings (MeSH) and text words. We searched MEDLINE (OVID and PubMed), Google Scholar, ISI Web of Science (Thom-on-Reuters), and the Cochrane Library (Wiley) from January 1995 to the present. To ensure literature saturation, we scanned the reference lists of included studies or relevant reviews identified through the search. Risk of Bias was assessed using the Newcastle-Ottawa scale for longitudinal studies and Cochrane risk-of-bias tool for randomized trials. (3) Results: abstracts of 75 articles were selected for full-text reading; after full-text reading, 44 articles were taken into consideration in the systematic review. 5 out of 7 in vitro experimental studies demonstrated antimicrobial activity against different species of bacteria and fungi. The use of SO as endotamponade associated with PPV led to better visual acuity and a lower rate of retinal detachment and the need for additional surgery. (4) Conclusions: Silicone oil reduces the risk of postoperative retinal detachment, especially in case of undetected retinal breaks, produces compartmentalization of the eye, may lead to early visual recovery, allows laser photocoagulation, prevents severe postoperative hypotony and has antimicrobic activity due to an inhibitory effect for several species of pathogens. Concerns regarding possible toxic effects on the retina and optic disc, compartmentalization and impaired washout of pathogen toxins have been reported. It may also influence intravitreal antibiotic distribution and clearance. Full article

(This article belongs to the Special Issue Recent Clinical Advances in Vitreoretinal Surgery)

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