Nanocomposite Materials for Drug Development and Biomedical Applications, Volume II

A special issue of Journal of Composites Science (ISSN 2504-477X). This special issue belongs to the section "Nanocomposites".

Deadline for manuscript submissions: closed (31 December 2021) | Viewed by 3185

Special Issue Editor


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Guest Editor
Department of Radiology, School of Medicine, Stanford University, Palo Alto, CA 94304, USA
Interests: nanocomposites; drug delivery; nanocompoistes for biomedical applications; cell therapy and bioscaffold development
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Special Issue Information

Dear Colleagues and Friends,

In the last few years, drug delivery and biomedical applications of nanocomposites have been emphasized by biomedical engineers, pharmaceutical scientists, and biotechnologists. Nanocomposite materials have unique properties to hold biomolecules, controlled release of the drug, supporting tissue and cells for regenerative medicine application. Drug delivery and tissue engineering application of nanocomposites are key research areas in the field of biomedical technlogy. This Special Issue will address problems related to synthesis and characterization of nanocomposites based on biopolymers and inorganic nanomaterials and application of such novel materials for local and drug delivery with controlled release, wound dressings, nanocomposite scaffold, and bone regeneration.

Dr. Bhaveah Kevadiya
Guest Editor

Manuscript Submission Information

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Keywords

  • Nanocomposites
  • Biopolymers
  • Inorganic nanomaterials
  • Drug delivery
  • Biomedical applications

Published Papers (1 paper)

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Research

12 pages, 3304 KiB  
Article
Role of Hybrid Nano-Zinc Oxide and Cellulose Nanocrystals on the Mechanical, Thermal, and Flammability Properties of Poly (Lactic Acid) Polymer
by Dilpreet S. Bajwa, Jamileh Shojaeiarani, Joshua D. Liaw and Sreekala G. Bajwa
J. Compos. Sci. 2021, 5(2), 43; https://0-doi-org.brum.beds.ac.uk/10.3390/jcs5020043 - 01 Feb 2021
Cited by 21 | Viewed by 2890
Abstract
Biopolymers with universal accessibility and inherent biodegradability can offer an appealing sustainable platform to supersede petroleum-based polymers. In this research, a hybrid system derived from cellulose nanocrystals (CNCs) and zinc oxide (ZnO) nanoparticles was added into poly (lactic acid) (PLA) to improve its [...] Read more.
Biopolymers with universal accessibility and inherent biodegradability can offer an appealing sustainable platform to supersede petroleum-based polymers. In this research, a hybrid system derived from cellulose nanocrystals (CNCs) and zinc oxide (ZnO) nanoparticles was added into poly (lactic acid) (PLA) to improve its mechanical, thermal, and flame resistance properties. The ZnO-overlaid CNCs were prepared via the solvent casting method and added to PLA through the melt-blending extrusion process. The composite properties were evaluated using SEM, a dynamic mechanical analyzer (DMA), FTIR TGA, and horizontal burning tests. The results demonstrated that the incorporation of 1.5% nano-CNC-overlaid ZnO nanoparticles into PLA enhanced the mechanical and thermal characteristics and the flame resistance of the PLA matrix. Oxidative combustion of CNC-ZnO promoted char formation and flame reduction. The shielding effect from the ZnO-CNC blend served as an insulator and resulted in noncontinuous burning, which increased the fire retardancy of nanocomposites. By contrast, the addition of ZnO into PLA accelerated the polymer degradation at higher temperature and shifted the maximum degradation to lower temperature in comparison with pure PLA. For PLA composites reinforced by ZnO, the storage modulus decreased with ZnO content possibly due to the scissoring effect of ZnO in the PLA matrix, which resulted in lower molecular weight. Full article
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