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Life
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Advances in Wrist Arthroplasty: From Biomechanics to Clinical Application
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Advances in Wrist Arthroplasty: From Biomechanics to Clinical Application

A special issue of Life (ISSN 2075-1729). This special issue belongs to the section "Medical Research".

Deadline for manuscript submissions: closed (15 January 2023) | Viewed by 8710

Special Issue Editors

Dr. Filippo Migliorini

E-Mail Website
Guest Editor
Department of Trauma and Reconstructive Surgery, RWTH University Hospital Aachen, Puwelsstrasse 30, 52074 Aachen, Germany
Interests: orthopedics; traumatology; meta-analysis; medical statistics; regenerative medicine; biomechanics
Special Issues, Collections and Topics in MDPI journals
Dr. Jörg Eschweiler

E-Mail Website
Guest Editor
1. Department of Trauma and Reconstructive Surgery, BG Hospital Bergmannstrost, Merseburgerstr. 165, 06112 Halle (Saale), Germany
2. Department of Trauma and Reconstructive Surgery, University Hospital Halle, Ernst-Grube-Str. 40, 06120 Halle (Saale), Germany
Interests: biomechanics; orthopedic surgery; bioengineering

Special Issue Information

Dear Colleagues,

Total wrist arthroplasty (TWA) for the treatment of pancarpal wrist arthritis attracts a broad interest. Problems such as implant fracture, instability, and prosthetic component loosening lead to unpredictable results, tempering the use of TWA in recent decades. However, thanks to advancements in implant design, surgical technique, patient selection, along with a deeper understanding of the wrist biomechanics, pitfalls, and expedients, the incidence of complications has dropped over the past decade.

This Special Issue aimed to provide the latest progresses achieved and to increase the evidence in TWA, touching on issues of biomechanics, implants, and clinical outcomes.

We welcome submissions of original research, comprehensive reviews perspectives, including, but not limited, to the following fields:

  • wrist biomechanics
  • wrist arthroplasty
  • implant designs
  • materials proprieties
  • patient selection
  • primary and revision settings

Dr. Filippo Migliorini
Dr. Jörg Eschweiler
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Life is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • wrist
  • arthroplasty
  • replacement
  • biomechanics
  • implants

Published Papers (4 papers)

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Research

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13 pages, 4881 KiB  
Article
Histomorphometry of Ossification in Functionalised Ceramics with Tripeptide Arg-Gly-Asp (RGD): An In Vivo Study
by Filippo Migliorini, Hanno Schenker, Nicola Maffulli, Frank Hildebrand and Jörg Eschweiler
Life 2022, 12(5), 761; https://0-doi-org.brum.beds.ac.uk/10.3390/life12050761 - 20 May 2022
Cited by 6 | Viewed by 1632
Abstract
The present study investigated the osseointegration promoted by functionalised ceramics with peptide Arg-Gly-Asp (RGD) in a rabbit model in vivo. Histomorphometry of the RGD functionalised ceramic implants was conducted by a trained pathologist to quantify the amount of mature and immature ossification at [...] Read more.
The present study investigated the osseointegration promoted by functionalised ceramics with peptide Arg-Gly-Asp (RGD) in a rabbit model in vivo. Histomorphometry of the RGD functionalised ceramic implants was conducted by a trained pathologist to quantify the amount of mature and immature ossification at the bone interface, and then compared to titanium alloy implants. The region of interest was the area surrounding the implant. The percentage of ROI covered by osteoid implant contact and mature bone implant contact were assessed. The presence of bone resorption, necrosis, and/or inflammation in the areas around the implant were quantitatively investigated. All 36 rabbits survived the experimental period of 6 and 12 weeks. All implants remained in situ. No necrosis, bone resorption, or inflammation were identified. At 12 weeks follow-up, the overall mean bone implant contact (p = 0.003) and immature osteoid contact (p = 0.03) were improved compared to the mean values evidenced at 6 weeks. At 6 weeks follow-up, the overall osteoid implant contact was greater in the RGD enhanced group compared to the titanium implant (p = 0.01). The other endpoints of interest were similar between the two implants at all follow-up points (p ≥ 0.05). Functionalised ceramics with peptide RGD promoted ossification in vivo. The overall osteoid and bone implant contact improved significantly from 6 to 12 weeks. Finally, RGD enhanced ceramic promoted faster osteoid implant contact in vivo than titanium implants. Overall, the amount of ossification at 12 weeks is comparable with the titanium implants. No necrosis, bone resorption, or inflammation were observed in any sample. Full article
(This article belongs to the Special Issue Advances in Wrist Arthroplasty: From Biomechanics to Clinical Application)
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9 pages, 1226 KiB  
Article
Total Wrist Arthroplasty for Posttraumatic Wrist Osteoarthritis: A Cohort Study Comparing Three Indications
by Matthias Holzbauer, Julian A. Mihalic, Michael Pollak and Stefan M. Froschauer
Life 2022, 12(5), 617; https://0-doi-org.brum.beds.ac.uk/10.3390/life12050617 - 21 Apr 2022
Cited by 3 | Viewed by 2060
Abstract
Scapholunate ligament ruptures and scaphoid nonunion with consecutive advanced collapse (SLAC and SNAC wrists) as well as intra-articular distal radius fractures (DRF) are prone to cause posttraumatic wrist osteoarthritis. The aim of this study was to compare the outcomes of these indications for [...] Read more.
Scapholunate ligament ruptures and scaphoid nonunion with consecutive advanced collapse (SLAC and SNAC wrists) as well as intra-articular distal radius fractures (DRF) are prone to cause posttraumatic wrist osteoarthritis. The aim of this study was to compare the outcomes of these indications for total wrist arthroplasty. We included 13, 11, and 8 patients with an overall mean age of 60 ± 9 years in the SLAC, SNAC, and DRF cohort, respectively. After an average follow-up period of 6 ± 3 years, we found no difference between our groups regarding pain levels and functional scores, although these parameters significantly improved compared to preoperative parameters. Complication and revision rates revealed no significant difference. However, significantly higher extension, arc of range of motion values in the flexion-extension, as well as in radial-ulnar deviation plain were detected in the SLAC compared to the DRF group. Finally, TWA proved to show a beneficial performance in all three investigated indications. Full article
(This article belongs to the Special Issue Advances in Wrist Arthroplasty: From Biomechanics to Clinical Application)
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3 pages, 172 KiB  
Comment
Comment on Eschweiler et al. Anatomy, Biomechanics, and Loads of the Wrist Joint. Life 2022, 12, 188
by Pantelis T. Nikolaidis and Jose Afonso
Life 2022, 12(8), 1166; https://0-doi-org.brum.beds.ac.uk/10.3390/life12081166 - 31 Jul 2022
Cited by 1 | Viewed by 831
Abstract
We have read ‘Anatomy, biomechanics and loads of the wrist joint’ [...] Full article
(This article belongs to the Special Issue Advances in Wrist Arthroplasty: From Biomechanics to Clinical Application)
7 pages, 1161 KiB  
Case Report
Wrist Hemiarthroplasty for Complex Intraarticular Distal Radius Fracture in a Patient with Manifest Osteoporosis
by Matthias Holzbauer, Leonard S. Bodell and Stefan M. Froschauer
Life 2022, 12(4), 471; https://0-doi-org.brum.beds.ac.uk/10.3390/life12040471 - 23 Mar 2022
Cited by 1 | Viewed by 2849
Abstract
Distal radius fracture (DRF) is one of the most common fractures of the elderly. The higher the degree of joint surface destruction, and the more adverse factors are involved, the more challenging proper treatment becomes. In this regard, osteoporosis as underlying systemic disease, [...] Read more.
Distal radius fracture (DRF) is one of the most common fractures of the elderly. The higher the degree of joint surface destruction, and the more adverse factors are involved, the more challenging proper treatment becomes. In this regard, osteoporosis as underlying systemic disease, chondropathy or degeneration of adjacent wrist bones as well as incompliance significantly impair the success of the chosen primary therapy. Wrist hemiarthroplasty has already been reported as primary or secondary procedure for DRFs. In this case report, we present a patient with a severely comminuted DRF including posttraumatic degeneration of the lunate as well as manifest osteoporosis. Wrist hemiarthroplasty using the ReMotion radius component in combination with proximal row carpectomy was performed as secondary surgery. This procedure proved to be a viable treatment option in terms of achieving low pain levels, high range of motion values and stable osteointegration over a course of 6.5 follow-up years. Full article
(This article belongs to the Special Issue Advances in Wrist Arthroplasty: From Biomechanics to Clinical Application)
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