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Biocompatibility Evaluation of Biomaterials

A special issue of Materials (ISSN 1996-1944). This special issue belongs to the section "Biomaterials".

Deadline for manuscript submissions: closed (31 March 2022) | Viewed by 3468

Special Issue Editor


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Guest Editor
Fondazione IRCCS Cà Granda Ospedale Maggiore Policlinico, Department of Biomedical, Surgical and Dental Sciences, University of Milan, 20133 Milan, Italy
Interests: implants; digital dentistry; bone augmentation; soft tissue management
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Following decades of improvements, dental implants have now become a reliable treatment option for the replacement of missing teeth in both partial and complete edentulous patients. Biocompatibility is formally defined as the ability of a material to elicit an appropriate biological response in a given application in the body.

In dentistry, research on the biocompatibility of new materials prior to their clinical application is much needed, as compounds may potentially damage the surrounding tissues, stimulating adverse reactions including toxicity, allergy or carcinogenicity, ultimately affecting the tissue renewal process and leading to the development and/or maintenance of exacerbated inflammatory responses.

This Special Issue will focus on the biocompatibility and bioactivity and clinical outcome of dental implants and their impact on clinical practice. Full papers of original articles, communications, and review articles are all welcome.

Dr. Mario Beretta
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Materials is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • biocompatibility
  • bioactivity, dental implants
  • clinical and radiographic evaluation
  • computer-aided bone regeneration

Published Papers (1 paper)

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Review

13 pages, 2880 KiB  
Review
Titanium Allergy Caused by Dental Implants: A Systematic Literature Review and Case Report
by Pier Paolo Poli, Fábio Vieira de Miranda, Tárik Ocon Braga Polo, Joel Ferreira Santiago Júnior, Tiburtino José Lima Neto, Bárbara Ribeiro Rios, Wirley Gonçalves Assunção, Edilson Ervolino, Carlo Maiorana and Leonardo Perez Faverani
Materials 2021, 14(18), 5239; https://0-doi-org.brum.beds.ac.uk/10.3390/ma14185239 - 12 Sep 2021
Cited by 14 | Viewed by 2985
Abstract
(1) Background: Hypersensitivity reactions to metals may arise in predisposed patients chronically exposed to metallic materials, including dental implants made of titanium alloys. The purpose of this article was to systematically review titanium allergy manifestations in patients treated with dental implants and report [...] Read more.
(1) Background: Hypersensitivity reactions to metals may arise in predisposed patients chronically exposed to metallic materials, including dental implants made of titanium alloys. The purpose of this article was to systematically review titanium allergy manifestations in patients treated with dental implants and report a clinical case; (2) Methods: A systematic electronic search was performed for articles published in the English language until July 2021. The following eligibility criteria were adopted: (1) Population: individuals undergoing titanium and/or titanium alloy implant-supported rehabilitations; (2) Exposure: peri-implant soft tissue reactions attributable to implant insertion; (3) Outcome: evidence of titanium allergy, diagnostic methods, and forms of resolution; (3) Results: The included studies, in summary, presented evidence that titanium should not be considered an inert material, being able to trigger allergic reactions, and may be responsible for implant failure. A 55-year-old male patient received 3 implants in the posterior region of the left mandible and presented an epulis-like lesion developed from the peri-implant mucosa. The immunohistochemical analysis of the biopsy specimen confirmed the initial diagnosis of allergic reaction to titanium; (4) Conclusions: Although the evidence is weak, and titanium allergy has a low incidence, hypersensitivity reactions should not be underestimated. A rapid and conclusive diagnosis is mandatory to prevent further complications. Full article
(This article belongs to the Special Issue Biocompatibility Evaluation of Biomaterials)
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