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Nano Particles and Fiber Reinforced Materials in Dentistry

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A special issue of Materials (ISSN 1996-1944). This special issue belongs to the section "Advanced Composites".

Deadline for manuscript submissions: closed (10 October 2023) | Viewed by 9469

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Prof. Dr. Paola Gandini

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Unit of Orthodontics and Paediatric Dentistry, Section of Dentistry, Department of Clinical, Surgical, Diagnostic and Paediatric Sciences, University of Pavia, 27100 Pavia, Italy
Interests: orthodontics; dentistry; dental materials; shear bond strength; enamel pretreatment; orthodontic miniscrews; computerized dentistry
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Prof. Dr. Andrea Scribante

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Guest Editor

Unit of Orthodontics and Paediatric Dentistry, Section of Dentistry, Department of Clinical, Surgical, Diagnostic and Paediatric Sciences, University of Pavia, 27100 Pavia, Italy
Interests: orthodontics; dental hygiene, adhesive dentistry; dental materials; CAD/CAM; intraoral scanner; computerized cast; shear; bond strength; bracket; fiber-reinforced composite; miniscrews; remineralization; probiotics; biomimetic materials
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

We are honored to announce a Special Issue of the Materials journal (IF 3.057) on “Nano Particles and Fiber Reinforced Materials in Dentistry.”

The reinforcement of composite dental materials with nanoparticles or fibers has been described in order to enhance mechanical properties and clinical performance of composites.

Nanoscience offers new possibilities for dental materials. Nanofillers with different size and shape are commonly used as dental restoratives.

Fiber reinforced materials based on carbon, polyaramid, polyethylene, and glass have been largely studied and, more recently, glass fibers of various compositions are more commonly applied as restorative and prosthetic materials.

These materials have been investigated with a particular focus on fracture strength, fatigue resistance, load-bearing capacity, flexural strength, compressive strength, bonding adhesion, layer thickness, bacterial adhesion, and clinical reliability.

With the introduction of new technologies, adhesion protocols, resin matrices, fibers, nanofillers, and application techniques, the reinforced-material field need further understanding.

In the light of the above, any progress in design, manufacturing, testing and clinical application is of great importance for further expansion of micro- and nano- filled polymers and fiber-reinforced composites for dental purposes.

Materials is preparing a Special Issue focused on reinforced materials for dental use.

Possible research topics include but are not limited to the keywords mentioned below. We kindly invite researchers, investigators, and clinicians to contribute with research studies, in vitro tests, case reports, clinical trials, and reviews that could improve the understanding of filled and reinforced dental materials.

Prof. Paola Gandini
Prof. Dr. Andrea Scribante
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Materials is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

adhesion
bacterial adhesion
bonding adhesion
buckling and warping
CAD/CAM materials
compressive strength
conservative dentistry
damage tolerance
delamination
dentistry
digital techniques
elastic couplings
fatigue resistance
fiber-reinforced composite
fillers
finite element modeling
flexural strength
fracture toughness
impact
layer thickness
load-bearing capacity
microfilled composite
nanocomposites
nanofilled composite
nanofillers
nondestructive testing
orthodontics
paediatric dentistry
polymer materials
polymer processing
prepreg
prosthodontics
spot bonding technique

Published Papers (4 papers)

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Research

15 pages, 3170 KiB

Open AccessArticle

Evaluating the Effect of Tideglusib-Loaded Bioactive Glass Nanoparticles as a Potential Dentine Regenerative Material

by Akhil C. Rao, K. Vijay Venkatesh, Vidyashree Nandini, Dhanasekaran Sihivahanan, Ahmed Alamoudi, Hammam Ahmed Bahammam, Sarah Ahmed Bahammam, Bassam Zidane, Maha A. Bahammam, Hitesh Chohan, Nassreen H. Albar, Pradeep Kumar Yadalam and Shankargouda Patil

Materials 2022, 15(13), 4567; https://0-doi-org.brum.beds.ac.uk/10.3390/ma15134567 - 29 Jun 2022

Cited by 3 | Viewed by 2017

Abstract

Dental pulp treatment is the least intrusive procedure currently available for preserving the vitality of the pulp. Several studies are underway to improve the bioactivity of pulp capping materials. Tideglusib isa potent anti-inflammatory, antioxidant, and a regenerative drug developed against Alzheimer’s disease and has been shown to be effective in the treatment of dental cavities. However, its bioactive properties encapsulated within the nanoparticles as a component of pulp capping material are largely unknown. In this study, tideglusib-loaded bioactive glass nanoparticles were synthesized (tideglusib-BgNPs) and mixed at various concentrations into the calcium silicate cement to testits physiomechanical and bioactivitiescompared with biodentine (control). The calcium silicate cement with 10wgt% tideglusib-BgNPs showed comparable physiomechanical properties to that of biodentine. Additionally, the assessment of cytotoxicity and bioactivity (cell proliferation, wound healing, and cell migration assays) showed increased bioactivity in terms of better wound healing, increased proliferation, and better migration of human dental pulp stem cells than biodentine. These findings suggest new opportunities to use tideglusib-BgNPs in pulp therapy. Full article

(This article belongs to the Special Issue Nano Particles and Fiber Reinforced Materials in Dentistry)

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19 pages, 1094 KiB

Open AccessArticle

Effect of Enamel Pretreatment with Pastes Presenting Different Relative Dentin Abrasivity (RDA) Values on Orthodontic Bracket Bonding Efficacy of Microfilled Composite Resin: In Vitro Investigation and Randomized Clinical Trial

by Maria Francesca Sfondrini, Maurizio Pascadopoli, Simone Gallo, Federico Ricaldone, Davide Dirk Kramp, Margherita Valla, Paola Gandini and Andrea Scribante

Materials 2022, 15(2), 531; https://0-doi-org.brum.beds.ac.uk/10.3390/ma15020531 - 11 Jan 2022

Cited by 6 | Viewed by 1946

Abstract

Bonding failure is a clinical issue frequently encountered in orthodontic practice. The aim of this study was to evaluate enamel pretreatment both in vitro and clinically using agents with different RDA values before brackets’ bonding, to assess if RDA can affect the Shear Bond Strength (SBS), Adhesive Remnant Index (ARI) and clinical failure rate of orthodontic brackets. For the in vitro study, 220 bovine teeth were pretreated with agents with different RDA values. Subsequently, brackets were bonded. For the clinical study, 20 patients underwent bonding of 20 brackets each with a split-mouth design. Low and high RDA toothpastes were used for enamel pretreatment. SBS, ARI and failures were recorded. Higher SBS values were found for teeth pretreated with lower RDA agents; conversely, lower SBS values were found for teeth pretreated with higher RDA agents (p < 0.05). For high ARI values, RDA increased too (p > 0.05). In the clinical study, a significantly lower failure rate was reported for teeth pretreated with low RDA toothpaste (2.5% in low RDA group, 7.0% in high RDA group; p < 0.05). No significant differences were assessed comparing the two dental arches and anterior and posterior sites. Enamel pretreatment with low RDA toothpastes could increase brackets’ survival rate. Further in vitro and clinical studies would be welcomed to confirm these findings. Full article

(This article belongs to the Special Issue Nano Particles and Fiber Reinforced Materials in Dentistry)

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15 pages, 3304 KiB

Open AccessArticle

Effect of Hydroxyapatite Microspheres, Amoxicillin–Hydroxyapatite and Collagen–Hydroxyapatite Composites on Human Dental Pulp-Derived Mesenchymal Stem Cells

by Yasmine Mendes Pupo, Lidiane Maria Boldrini Leite, Alexandra Cristina Senegaglia, Liziane Antunes, Jessica Mendes Nadal, Eliane Leal de Lara, Rafael Eiji Saito, Sandra Regina Masetto Antunes, William Fernandes Lacerda and Paulo Vitor Farago

Materials 2021, 14(24), 7515; https://0-doi-org.brum.beds.ac.uk/10.3390/ma14247515 - 08 Dec 2021

Cited by 4 | Viewed by 2356

Abstract

In this study, the preparation and characterization of three hydroxyapatite-based bioactive scaffolds, including hydroxyapatite microspheres (HAps), amoxicillin–hydroxyapatite composite (Amx–HAp), and collagen–hydroxyapatite composite (Col–HAp) were performed. In addition, their behavior in human dental pulp mesenchymal stem cell (hDPSC) culture was investigated. HAps were synthesized through the following methods: microwave hydrothermal, hydrothermal reactor, and precipitation, respectively. hDPSCs were obtained from samples of third molars and characterized by immunophenotypic analysis. Cells were cultured on scaffolds with osteogenic differentiation medium and maintained for 21 days. Cytotoxicity analysis and migration assay of hDPSCs were evaluated. After 21 days of induction, no differences in genes expression were observed. hDPSCs highly expressed the collagen IA and the osteonectin at the mRNA. The cytotoxicity assay using hDPSCs demonstrated that the Col–HAp group presented non-viable cells statistically lower than the control group (p = 0.03). In the migration assay, after 24 h HAps revealed the same migration behavior for hDPSCs observed compared to the positive control. Col–HAp also provided a statistically significant higher migration of hDPSCs than HAps (p = 0.02). Migration results after 48 h for HAps was intermediate from those achieved by the control groups. There was no statistical difference between the positive control and Col–HAp. Specifically, this study demonstrated that hydroxyapatite-based bioactive scaffolds, especially Col-Hap, enhanced the dynamic parameters of cell viability and cell migration capacities for hDPSCs, resulting in suitable adhesion, proliferation, and differentiation of this osteogenic lineage. These data presented are of high clinical importance and hold promise for application in therapeutic areas, because Col–HAp can be used in ridge preservation, minor bone augmentation, and periodontal regeneration. The development of novel hydroxyapatite-based bioactive scaffolds with clinical safety for bone formation from hDPSCs is an important yet challenging task both in biomaterials and cell biology. Full article

(This article belongs to the Special Issue Nano Particles and Fiber Reinforced Materials in Dentistry)

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18 pages, 12295 KiB

Open AccessArticle

Evaluation of the Behavior of Two CAD/CAM Fiber-Reinforced Composite Dental Materials by Immersion Tests

by Farah Bechir, Simona Maria Bataga, Adrian Tohati, Elena Ungureanu, Cosmin Mihai Cotrut, Edwin Sever Bechir, Mircea Suciu and Diana Maria Vranceanu

Materials 2021, 14(23), 7185; https://0-doi-org.brum.beds.ac.uk/10.3390/ma14237185 - 25 Nov 2021

Cited by 11 | Viewed by 1993

Abstract

Fiber-reinforced composites are used as restorative materials for prosthetic oral rehabilitation. Gastroesophageal reflux disease (GERD) is an accustomed affection with various oral manifestations. This study aimed to evaluate the behavior of two high-performance CAD/CAM milled reinforced composites (Trinia™, TriLor) in artificial saliva at different pH levels through immersion tests, and to determine if changes in mass or surface morphology at variable pH, specific for patients affected by GERD, appear. After investigating the elemental composition and surface morphology, the specimens were immersed in Carter Brugirard artificial saliva for 21 days at different pH values (5.7, 7.6, and varying the pH from 5.7 to 3). The values of the weighed masses during the immersion tests were statistically processed in terms of mean and standard deviation. Results suggested that irrespective of the medium pH, the two composites presented a similar mass variation in the range of −0.18 (±0.01)–1.82 (±0.02) mg after immersion, suggesting their stability when in contact with artificial saliva, an aspect which was also highlighted by scanning electron microscope (SEM) analysis performed on the immersed surfaces. Novel composite biomaterials can be a proper alternative for metal alloys used for prosthetic frameworks in patients suffering from GERD. Full article

(This article belongs to the Special Issue Nano Particles and Fiber Reinforced Materials in Dentistry)

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