Search for Articles:
Title / Keyword
Author / Affiliation / Email
Journal
Article Type
 
 
Advanced Search
 
Section
Special Issue
Volume
Issue
Number
Page
 
5.2
3.4
Journals
Materials
Special Issues
Micro/Nano Materials, Devices, and Systems for Biomedical Applications
materials-logo
Submit to Materials Review for Materials Propose a Special Issue

Journal Menu

► Journal Menu

Journal Browser

► Journal Browser
share announcement

Micro/Nano Materials, Devices, and Systems for Biomedical Applications

A special issue of Materials (ISSN 1996-1944). This special issue belongs to the section "Biomaterials".

Deadline for manuscript submissions: closed (20 July 2023) | Viewed by 3165

Special Issue Editors

Prof. Dr. Jungkwun Kim

E-Mail Website
Guest Editor
Kansas State University, Manhattan, KS 66506, USA
Interests: micro/nano 3D fabrication; implantable micro sensors
Prof. Dr. Albert Kim

E-Mail Website
Guest Editor
Department of Medical Engineering, University of South Florida, Tampa, FL 33620, USA
Interests: BioMEMS; implantable micro devices

Special Issue Information

Dear Colleagues,

We are pleased to present a Special Issue of Materials (MDPI) entitled “Micro/Nano Materials, Devices, and Systems for Biomedical Applications”, in which we are seeking original and seminal contributions on biomedical sensors and systems, such as on implantable wireless microsystems, nanotechnologies for chemical/biological analysis and bioenergy harvesting, wearable healthcare systems, and point-of-care diagnostic devices based on innovative approaches of micro/nano fabrication. The scale of development of micro- and nanoscale sensors have led to the rapid expansion of Materials as researchers publish their latest findings. The developed micro/nano devices and systems have, in turn, enabled researchers to establish biological and chemical analyses and to improve treatment in precisely controlled micro- and nanoenvironments, across a range of scales from a single DNA molecule to the whole body.

The integrated, novel designs of devices and systems using micro-/nanotechnology will enable to discovery of new solutions for engineering and scientific challenges in bioscience and bioengineering. Micro-/nanoresolution platforms associated with fabrication techniques will enhance interfacing and understanding of the scientific and engineering challenges of various biological approaches, with ease of manipulation and monitoring with high sensitivity and specificity. Combinative approaches based on multidisciplinary fields of electrical engineering, chemical engineering, and mechanical engineering in biology, materials science, and analytical chemistry will accelerate advancements in the field of biomaterials and biotechnology.

Review and research articles on the highlighted research topics are welcome for submission to this Special Issue, with the overall aim of relating the key issues of basic or applied research in biotechnological applications.

Prof. Dr. Jungkwun Kim
Prof. Dr. Albert Kim
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Materials is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • biomedical micro/nano sensors and systems
  • implantable wireless microsystems
  • nanotechnology for chemical/biological analysis and bioenergy harvesting
  • wearable healthcare systems
  • point-of-care diagnostic devices
  • micro/nano 3D fabrication

Published Papers (2 papers)

Download All Papers
Order results
Result details
Show export options expand_more Show export options expand_less
Select all
Export citation of selected articles as:

Research

19 pages, 5269 KiB  
Article
Laser Ablated Albumin Functionalized Spherical Gold Nanoparticles Indicated for Stem Cell Tracking
by Dilcele Silva Moreira Dziedzic, Bassam Felipe Mogharbel, Ana Carolina Irioda, Priscila Elias Ferreira Stricker, Thiago Demetrius Woiski, Thiago Neves Machado, Arandi Ginane Bezerra Jr and Katherine Athayde Teixeira de Carvalho
Materials 2023, 16(3), 1034; https://0-doi-org.brum.beds.ac.uk/10.3390/ma16031034 - 24 Jan 2023
Cited by 1 | Viewed by 1160
Abstract
Cell tracking in cell-based therapy applications helps distinguish cell participation among paracrine effect, neovascularization, and matrix deposition. This preliminary study examined the cellular uptake of gold nanoparticles (AuNPs), observing cytotoxicity and uptake of different sizes and AuNPs concentrations in Adipose-derived stromal cells (ASCs). [...] Read more.
Cell tracking in cell-based therapy applications helps distinguish cell participation among paracrine effect, neovascularization, and matrix deposition. This preliminary study examined the cellular uptake of gold nanoparticles (AuNPs), observing cytotoxicity and uptake of different sizes and AuNPs concentrations in Adipose-derived stromal cells (ASCs). ASCs were incubated for 24 h with Laser ablated Albumin functionalized spherical AuNPs (LA-AuNPs), with average sizes of 2 nm and 53 nm in diameter, in four concentrations, 127 µM, 84 µM, 42 µM, and 23 µM. Cytotoxicity was examined by Live/Dead assay, and erythrocyte hemolysis, and the effect on the cytoskeleton was investigated by immunocytochemistry for β-actin. The LA-AuNPs were internalized by the ASCs in a size and concentration-dependent manner. Clusters were observed as dispersed small ones in the cytosol, and as a sizeable perinuclear cluster, without significant harmful effects on the cells for up to 2 weeks. The Live/Dead and hemolysis percentage results complemented the observations that the larger 53 nm LA-AuNPs in the highest concentrated solution significantly lowered cell viability. The demonstrated safety, cellular uptake, and labelling persistency with LA-AuNPs, synthesized without the combination of chemical solutions, support their use for cell tracking in tissue engineering applications. Full article
(This article belongs to the Special Issue Micro/Nano Materials, Devices, and Systems for Biomedical Applications)
►▼ Show Figures

Figure 1

14 pages, 3973 KiB  
Article
Experimental Validation of Diffraction Lithography for Fabrication of Solid Microneedles
by Jun Ying Tan, Yuankai Li, Faraz Chamani, Aabila Tharzeen, Punit Prakash, Balasubramaniam Natarajan, Rahul A. Sheth, Won Min Park, Albert Kim, Donghoon Yoon and Jungkwun Kim
Materials 2022, 15(24), 8934; https://0-doi-org.brum.beds.ac.uk/10.3390/ma15248934 - 14 Dec 2022
Cited by 4 | Viewed by 1395
Abstract
Microneedles are highly sought after for medicinal and cosmetic applications. However, the current manufacturing process for microneedles remains complicated, hindering its applicability to a broader variety of applications. As diffraction lithography has been recently reported as a simple method for fabricating solid microneedles, [...] Read more.
Microneedles are highly sought after for medicinal and cosmetic applications. However, the current manufacturing process for microneedles remains complicated, hindering its applicability to a broader variety of applications. As diffraction lithography has been recently reported as a simple method for fabricating solid microneedles, this paper presents the experimental validation of the use of ultraviolet light diffraction to control the liquid-to-solid transition of photosensitive resin to define the microneedle shape. The shapes of the resultant microneedles were investigated utilizing the primary experimental parameters including the photopattern size, ultraviolet light intensity, and the exposure time. Our fabrication results indicated that the fabricated microneedles became taller and larger in general when the experimental parameters were increased. Additionally, our investigation revealed four unique crosslinked resin morphologies during the first growth of the microneedle: microlens, first harmonic, first bell-tip, and second harmonic shapes. Additionally, by tilting the light exposure direction, a novel inclined microneedle array was fabricated for the first time. The fabricated microneedles were characterized with skin insertion and force-displacement tests. This experimental study enables the shapes and mechanical properties of the microneedles to be predicted in advance for mass production and wide practical use for biomedical or cosmetic applications. Full article
(This article belongs to the Special Issue Micro/Nano Materials, Devices, and Systems for Biomedical Applications)
►▼ Show Figures

Figure 1

Show export options expand_more Show export options expand_less
Select all
Export citation of selected articles as:
 
Displaying articles 1-2
Back to TopTop