materials-logo

Journal Browser

Journal Browser

Advances in Biomaterials: Design, Synthesis, Characterisation and Biomedical Application

A special issue of Materials (ISSN 1996-1944). This special issue belongs to the section "Biomaterials".

Deadline for manuscript submissions: closed (31 January 2021) | Viewed by 9822

Special Issue Editors


E-Mail Website
Guest Editor
1. School of Mechanical and Manufacturing Engineering, Dublin City University, D09 NA55 Dublin, Ireland
2. Centre for Medical Engineering Research, Dublin City University, D09 NA55 Dublin, Ireland
Interests: biomaterials; tissue engineering; tissue regeneration; drug delivery; biomedical engineering
Special Issues, Collections and Topics in MDPI journals

E-Mail Website
Guest Editor
School of Mechanical and Manufacturing Engineering, Dublin City University, D09 NA55 Dublin, Ireland
Interests: cartilage; tissue engineering; scaffolds; bone repair; biomaterials; bioprinting
Special Issues, Collections and Topics in MDPI journals

E-Mail Website
Guest Editor
School of Pharmacy, Queen’s University Belfast, 97 Lisburn Rd., Belfast BT9 7BL, UK
Interests: nanomedicine; gene therapy; nucleic acids; oncology; wound healing and mRNA and DNA vaccination
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear colleagues,

We would like to invite you to contribute a short communication, full article or review to this Special Issue, entitled “Advances in Biomaterials: Design, Synthesis, Characterisation and Biomedical Application”.

Biomaterials that interface with biological systems are used to prevent, detect and treat disease; to deliver drugs safely and efficiently; to support the body as it heals; and to engineer functional tissues outside of the body for organ replacement. In recent years, the research topic has progressed beyond simply selecting materials that were initially designed for other engineering applications with a primary focus on properties that enabled restoration of function and mitigation of acute pathology. Biomaterials are now realistically designed with controlled architecture and dynamic functionality to enable integration with biological complexity and achieve tailored, high-level functions in the body. The changeover has been from the use of biomaterials that are merely tolerated by the body to promoting biomaterials that are no longer bioinert but bioactive and bioresponsive. This viewpoint takes into account recent developments in the field of hard and soft biomaterials, with a specific emphasis on advances in multiscale control, static to dynamic functionality, hierarchical biocomplex materials (e.g., cellular and composite architectures, adaptive growth, and as well as remodelling) and innovative manufacture techniques to enable patient-specific device performance.

The focus of this Special Issue will provide the community with the opportunity to present the latest fundamental and applied biomaterials research to the broader materials community. Materials publishes manuscripts which advance the in-depth understanding of the relationship between the structure, properties and functions of all kinds of materials and covers all aspects of biomaterials research across the pipeline of design, synthesis, characterisation and application. This Special Issue will also facilitate the important interactions between the biomaterials community and the broader materials communities.

Prof. Dr. Nicholas Dunne
Dr. Tanya Levingstone
Prof. Dr. Helen McCarthy
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Materials is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • Biomaterials
  • Polymers
  • Metals
  • Ceramics
  • Composites
  • Design
  • Synthesis
  • Characterisation and testing
  • Manufacturing processes
  • Additive manufacturing
  • Biomedical application
  • Structure–property relationships
  • Surface modification
  • Cell–material interaction
  • Host response
  • Medical devices
  • Drug delivery systems
  • Tissue engineering
  • Regenerative medicine

Published Papers (3 papers)

Order results
Result details
Select all
Export citation of selected articles as:

Research

Jump to: Review

17 pages, 2724 KiB  
Article
Biomimetic Polymer Surfaces by High Resolution Molding of the Wings of Different Cicadas
by Graham Reid, James C. McCormack, Olivier Habimana, Fabian Bayer, Catherine Goromonzi, Eoin Casey, Aidan Cowley and Susan M. Kelleher
Materials 2021, 14(8), 1910; https://0-doi-org.brum.beds.ac.uk/10.3390/ma14081910 - 11 Apr 2021
Cited by 11 | Viewed by 2954
Abstract
Recent studies have shown that insect wings have evolved to have micro- and nanoscale structures on the wing surface, and biomimetic research aims to transfer such structures to application-specific materials. Herein, we describe a simple and cost-effective method of replica molding the wing [...] Read more.
Recent studies have shown that insect wings have evolved to have micro- and nanoscale structures on the wing surface, and biomimetic research aims to transfer such structures to application-specific materials. Herein, we describe a simple and cost-effective method of replica molding the wing topographies of four cicada species using UV-curable polymers. Different polymer blends of polyethylene glycol diacrylate and polypropylene glycol diacrylate were used as molding materials and a molding chamber was designed to precisely control the x, y, and z dimensions. Analysis by scanning electron microscopy showed that structures ranged from 148 to 854 nm in diameter, with a height range of 191–2368 nm, and wing patterns were transferred with high fidelity to the crosslinked polymer. Finally, bacterial cell studies show that the wing replicas possess the same antibacterial effect as the cicada wing from which they were molded. Overall, this work shows a quick and simple method for patterning UV-curable polymers without the use of expensive equipment, making it a highly accessible means of producing microstructured materials with biological properties. Full article
Show Figures

Figure 1

13 pages, 1818 KiB  
Article
Understanding Electrodeposition of Chitosan–Hydroxyapatite Structures for Regeneration of Tubular-Shaped Tissues and Organs
by Katarzyna Nawrotek and Jacek Grams
Materials 2021, 14(5), 1288; https://0-doi-org.brum.beds.ac.uk/10.3390/ma14051288 - 08 Mar 2021
Cited by 13 | Viewed by 1707
Abstract
Tubular-shaped hydrogel structures were obtained in the process of cathodic electrodeposition from a chitosan–hydroxyapatite solution carried out in a cylindrical geometry. The impact of the initial concentration of solution components (i.e., chitosan, hydroxyapatite, and lactic acid) and process parameters (i.e., time and voltage) [...] Read more.
Tubular-shaped hydrogel structures were obtained in the process of cathodic electrodeposition from a chitosan–hydroxyapatite solution carried out in a cylindrical geometry. The impact of the initial concentration of solution components (i.e., chitosan, hydroxyapatite, and lactic acid) and process parameters (i.e., time and voltage) on the mass and structural properties of deposit was examined. Commercially available chitosan differs in average molecular weight and deacetylation degree; therefore, these parameters were also studied. The application of Fourier-transform infrared spectroscopy, scanning electron microscopy, and time-of-flight secondary ion mass spectrometry allowed obtaining fundamental information about the type of bonds and interactions created in electrodeposited structures. Biocompatible tubular implants are highly desired in the field of regeneration or replacement of tubular-shaped tissues and organs; therefore, the possibility of obtaining deposits with the desired structural properties is highly anticipated. Full article
Show Figures

Graphical abstract

Review

Jump to: Research

23 pages, 5148 KiB  
Review
Characterization of Hybrid Materials Prepared by Sol-Gel Method for Biomedical Implementations. A Critical Review
by Michelina Catauro and Stefano Vecchio Ciprioti
Materials 2021, 14(7), 1788; https://0-doi-org.brum.beds.ac.uk/10.3390/ma14071788 - 05 Apr 2021
Cited by 33 | Viewed by 4234
Abstract
The interaction between tissues and biomaterials (BM) has the purpose of improving and replacing anatomical parts of the human body, avoiding the occurrence of adverse reactions in the host organism. Unfortunately, the early failure of implants cannot be currently avoided, since neither a [...] Read more.
The interaction between tissues and biomaterials (BM) has the purpose of improving and replacing anatomical parts of the human body, avoiding the occurrence of adverse reactions in the host organism. Unfortunately, the early failure of implants cannot be currently avoided, since neither a good mixture of mechanical and chemical characteristics of materials nor their biocompatibility has been yet achieved. Bioactive glasses are recognized to be a fine class of bioactive substances for good repair and replacement. BM interact with living bones through the formation of a hydroxyapatite surface layer that is analogous to bones. Bioglasses’ composition noticeably affects their biological properties, as does the synthesis method, with the best one being the versatile sol-gel technique, which includes the change of scheme from a ‘sol’ fluid into a ‘gel’. This process is widely used to prepare many materials for biomedical implants (e.g., hip and knee prostheses, heart valves, and ceramic, glassy and hybrid materials to serve as carriers for drug release). Nanoparticles prepared by the sol-gel method are interesting systems for biomedical implementations, and particularly useful for cancer therapy. This review provides many examples concerning the synthesis and characterization of the above-mentioned materials either taken from literature and from recently prepared zirconia/polyethylene glycol (PEG) hybrids, and the corresponding results are extensively discussed. Full article
Show Figures

Graphical abstract

Back to TopTop