Special Issue "Novel Biomaterials and Technology for Dental Clinical Applications"
Deadline for manuscript submissions: 20 November 2021.
Interests: morphology of dental tissues; restorative and esthetic dentistry; biomaterials; electron microscopy; immunohistochemistry; regenerative dentistry; nanotechnology; stem Cells; randomized clinical trial
Recent advances in biomaterials, tissue engineering and nanotechnology for dental clinical applications represent an important challenge for daily practice. Dental diseases often can lead to partial or complete damage to dental structures. Thus, the use of modern technologies with innovative and sophisticated biomaterials are fundamental for all kinds of dental care.
In restorative dentistry, nanotechnologies can develop aesthetic materials with ameliorated properties to increase the longevity of restorations. In endodontics, nanomaterials can deliver growth factors and stem cells, stimulating the regenerative capacity of the dentin-pulp complex. Current treatments using dental implants in association with scaffolds, stem cells, and growth factors may enhance osseointegration and host tissue response. Moreover, prevention strategies for reducing caries incidence, periodontal disease, and oral cancer are strongly needed, as well as controlling the side effects produced by different materials (such as bleaching agents, resin methacrylates, and other nano-featured compounds). Modern developments of tissue engineering platforms, including spheroids, organoids, microfluidics, and organ-on-chip technologies, have paved the way for creating excellent tools simulating the oral environment, for a better understanding of the regenerative processes. Promising stem cell-based approaches for re-creating fully functional dental tissues are ongoing, offering exciting perspectives, that, hopefully, will soon be ready for clinical applications. Thus, the present topic would like to focus on the progress of contemporary materials coupled with biological and/or technological platforms for successful daily practice in all fields of dentistry, including craniofacial bone regeneration procedures.
Prof. Giovanna Orsini
Manuscript Submission Information
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- stem cells
- tissue engineering
- clinical trials