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Novel Advances and Approaches in Biomedical Materials Based on Calcium Phosphates (Second Volume)

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A special issue of Materials (ISSN 1996-1944). This special issue belongs to the section "Biomaterials".

Deadline for manuscript submissions: closed (20 February 2022) | Viewed by 7055

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Dear Colleagues,

Research into the use of calcium phosphates in the development and clinical application of biomedical materials has been a very diverse activity undertaken by a wide range of scientists, engineers, and medical practitioners, among others. This field of research can hence be truly defined as interdisciplinary, and a great deal of interesting work leading to imaginative and innovative solutions for the improvement of health outcomes is ongoing. Earlier, we ran a special issue on this (Novel Advances and Approaches in Biomedical Materials Based on Calcium Phosphates) and this attracted some excellent and interesting papers. Due to the success of this and the fact that this research area is constantly being added to with extremely interesting and topical papers, it was decided to run it again as a second volume.

It is hence the intention of this Special Issue to provide a further selection of the wide range of the current advances in this area. We thus invite contributions to this Issue in the form of original articles, review articles, research notes, and short communications from various areas of this scientific discipline. Areas of interest that could be covered include contributions based on the uses of natural by products or repurposed materials to form potential biomaterials, novel composites of calcium phosphates with other materials, chemical manipulations of calcium phosphates that lead to novel biomaterials, studies advancing the cell biology surrounding the incorporation of calcium phosphate biomaterials, engineering/biomechanical aspects of using calcium phosphate biomaterials, and human or animal clinical studies involving calcium phosphates. Studies on novel approaches to characterization to study these materials would also be of interest. We also welcome contributions from those involved in regulating the use of calcium phosphate biomaterials. Hence, we invite scientists, engineers, doctors, and medical device regulators to submit articles of interest.

It is hoped that a second volume of this Special Issue will further attract submissions of the very diverse topics that characterise this area of study and hence provide more examples of the exciting advances in research associated with the biomedical materials theme.

We look forward to your contributions. Each article will be subject to rigorous peer review.

Assoc. Prof. Dr. Michael R. Mucalo
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Materials is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

calcium phosphate
hydroxyapatite
characterization
regulation
natural matrices
clinical use
orthopedics
xenografts
medical devices

Published Papers (2 papers)

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Research

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21 pages, 24633 KiB

Open AccessArticle

Characterization of Tetracalcium Phosphate/Monetite Biocement Modified by Magnesium Pyrophosphate

by Radoslava Stulajterova, Lubomir Medvecky, Maria Giretova, Tibor Sopcak, Lenka Luptakova, Radovan Bures and Eva Szekiova

Materials 2022, 15(7), 2586; https://0-doi-org.brum.beds.ac.uk/10.3390/ma15072586 - 31 Mar 2022

Cited by 2 | Viewed by 1644

Abstract

Magnesium pyrophosphate modified tetracalcium phosphate/monetite cement mixtures (MgTTCPM) were prepared by simple mechanical homogenization of compounds in a ball mill. The MgP₂O₇ was chosen due to the suitable setting properties of the final cements, in contrast to cements with the addition of amorphous (Ca, Mg) CO₃ or newberite, which significantly extended the setting time even in small amounts (corresponding ~to 1 wt% of Mg in final cements). The results showed the gradual dissolution of the same amount of Mg₂P₂O₇ phase, regardless of its content in the cement mixtures, and the refinement of formed HAP nanoparticles, which were joined into weakly and mutually bound spherical agglomerates. The compressive strength of composite cements was reduced to 14 MPa and the setting time was 5–10 min depending on the composition. Cytotoxicity of cements or their extracts was not detected and increased proliferative activity of mesenchymal stem cells with upregulation of osteopontin and osteonectin genes was verified in cells cultured for 7 and 15 days in cement extracts. The above facts, including insignificant changes in the pH of simulated body fluid solution and mechanical strength close to cancellous bone, indicate that MgTTCPM cement mixtures could be suitable biomaterials for use in the treatment of bone defects. Full article

(This article belongs to the Special Issue Novel Advances and Approaches in Biomedical Materials Based on Calcium Phosphates (Second Volume))

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37 pages, 2833 KiB

Open AccessFeature PaperReview

The Use of Calcium Phosphates in Cosmetics, State of the Art and Future Perspectives

by Francesca Carella, Lorenzo Degli Esposti, Alessio Adamiano and Michele Iafisco

Materials 2021, 14(21), 6398; https://0-doi-org.brum.beds.ac.uk/10.3390/ma14216398 - 25 Oct 2021

Cited by 24 | Viewed by 4940

Abstract

Calcium phosphates (CaPs) belong to a class of biomimetic materials widely employed for medical applications thanks to their excellent properties, such as biodegradability, biocompatibility and osteoinductivity. The recent trend in the cosmetics field of substituting potentially hazardous materials with natural, safe, and sustainable ingredients for the health of consumers and for the environment, as well as the progress in the materials science of academics and chemical industries, has opened new perspectives in the use of CaPs in this field. While several reviews have been focused on the applications of CaP-based materials in medicine, this is the first attempt to catalogue the properties and use of CaPs in cosmetics. In this review a brief introduction on the chemical and physical characteristics of the main CaP phases is given, followed by an up-to-date report of their use in cosmetics through a large literature survey of research papers and patents. The application of CaPs as agents in oral care, skin care, hair care, and odor control has been selected and extensively discussed, highlighting the correlation between the chemical, physical and toxicological properties of the materials with their final applications. Finally, perspectives on the main challenges that should be addressed by the scientific community and cosmetics companies to widen the application of CaPs in cosmetics are given. Full article

(This article belongs to the Special Issue Novel Advances and Approaches in Biomedical Materials Based on Calcium Phosphates (Second Volume))

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