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Carbon-Based Materials and Nanotechnology for Biomedicine and Tissue Engineering

A special issue of Materials (ISSN 1996-1944). This special issue belongs to the section "Advanced Nanomaterials and Nanotechnology".

Deadline for manuscript submissions: closed (31 March 2022) | Viewed by 2779

Special Issue Editor


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Guest Editor
Department of Nanobiotechnology, Warsaw University of Life Sciences, Warsaw, Poland
Interests: graphene; carbon nanostructures; cancer; cytotoxicity; cytochrome P450; hepatotoxicity

Special Issue Information

Dear Colleagues,

In recent years, carbon-based materials have gained a great amount of attention in research and industry. The great variability of nanostructures composed of carbon allotropic forms creates new possibilities for applications in different fields of biomedicine. The research includes the development of drug delivery platforms for cancer therapies, innovative scaffolds for cell cultures and tissue engineering, antibacterial coatings, and many more. Along with the increasing numbers of potential applications, new compositions, and synthesis methods, the number of safety issues is growing as well, and further studies are necessary to establish the relationship between carbon-based materials and biological systems. To study the influence of these factors, continuous research efforts are needed to solve the many critical issues that remain, such as biocompatibility or long-term health effects.

The forthcoming Special Issue on “Carbon-Based Materials and Nanotechnology for Biomedicine and Tissue Engineering” aims to collect and publish original research manuscripts that either add knowledge to our current understanding of the characterization of properties of carbon-based nanostructures, materials, and their nanocomposites or report new applications of these very promising materials, especially concerning biomedical applications and safety issues. Critical reviews are also welcome.

It is my pleasure to invite you to provide a valuable contribution to this Special Issue.

Dr. Barbara Strojny-Cieslak
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Materials is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • Carbon allotropes 
  • Graphene family materials 
  • Biomedicine 
  • Cancer research 
  • Biocompatibility 
  • Toxicity 
  • Tissue engineering 
  • Scaffolds

Published Papers (1 paper)

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Research

18 pages, 10169 KiB  
Article
Comparison of the Toxicity of Pristine Graphene and Graphene Oxide, Using Four Biological Models
by Sławomir Jaworski, Barbara Strojny-Cieślak, Mateusz Wierzbicki, Marta Kutwin, Ewa Sawosz, Maciej Kamaszewski, Arkadiusz Matuszewski, Malwina Sosnowska, Jarosław Szczepaniak, Karolina Daniluk, Agata Lange, Michał Pruchniewski, Katarzyna Zawadzka, Maciej Łojkowski and Andre Chwalibog
Materials 2021, 14(15), 4250; https://0-doi-org.brum.beds.ac.uk/10.3390/ma14154250 - 29 Jul 2021
Cited by 13 | Viewed by 2382
Abstract
There are numerous applications of graphene in biomedicine and they can be classified into several main areas: delivery systems, sensors, tissue engineering and biological agents. The growing biomedical field of applications of graphene and its derivates raises questions regarding their toxicity. We will [...] Read more.
There are numerous applications of graphene in biomedicine and they can be classified into several main areas: delivery systems, sensors, tissue engineering and biological agents. The growing biomedical field of applications of graphene and its derivates raises questions regarding their toxicity. We will demonstrate an analysis of the toxicity of two forms of graphene using four various biological models: zebrafish (Danio rerio) embryo, duckweed (Lemna minor), human HS-5 cells and bacteria (Staphylococcus aureus). The toxicity of pristine graphene (PG) and graphene oxide (GO) was tested at concentrations of 5, 10, 20, 50 and 100 µg/mL. Higher toxicity was noted after administration of high doses of PG and GO in all tested biological models. Hydrophilic GO shows greater toxicity to biological models living in the entire volume of the culture medium (zebrafish, duckweed, S. aureus). PG showed the highest toxicity to adherent cells growing on the bottom of the culture plates—human HS-5 cells. The differences in toxicity between the tested graphene materials result from their physicochemical properties and the model used. Dose-dependent toxicity has been demonstrated with both forms of graphene. Full article
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