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Micro- and Nanoparticles in Biomedical and Cosmetic Applications

A special issue of Materials (ISSN 1996-1944). This special issue belongs to the section "Biomaterials".

Deadline for manuscript submissions: closed (20 April 2022) | Viewed by 8962

Special Issue Editor


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Guest Editor
Department of Chemistry of Biomaterials and Cosmetics, Faculty of Chemistry, Nicolaus Copernicus University in Torun, Gagarina 7, 87-100 Torun, Poland
Interests: microparticles; nanoparticles; encapsulation techniques; controlled release; biopolymers; polymeric materials; biomaterials; composites; cosmetic chemistry
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Special Issue Information

Dear Colleagues,

In the biomedical and cosmetics fields, micro- and nanotechnology has enormous potential, and micro-/nanoparticles are already being used in both medicine and the pharmaceutical industry.

Nano- and microparticles are applied in the delivery of drugs, proteins, genes, vaccines, polypeptides, nucleic acids, etc. They are indispensable tools in disease monitoring and therapy. In cosmetics, nanoscale versions of ingredients are used to provide more efficient transport of the ingredients through the skin and long-lasting effects. Many active compounds, such as vitamins and plant extracts, are encapsulated in microparticulate delivery systems to achieve improved stability and bioavailability in skin delivery. The number of publications on micro- and nanoparticles has risen fast over the last few years, making this an exciting and promising area of science.

This Special Issue will focus on novel advances and applications of micro- and nanoparticles in biomedical and cosmetics fields.  Full research articles and comprehensive review articles are welcome.

Dr. Justyna Kozlowska
Guest Editor

Manuscript Submission Information

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Keywords

  • micro/nanoparticles
  • micro/nanocapsules
  • micro/nanospheres
  • liposomes
  • encapsulation
  • biomedical applications
  • cosmetics
  • active ingredients
  • delivery system

Published Papers (3 papers)

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Research

16 pages, 4575 KiB  
Article
The Influence of Nanometals, Dispersed in the Electrophoretic Nanohydroxyapatite Coatings on the Ti13Zr13Nb Alloy, on Their Morphology and Mechanical Properties
by Michał Bartmański, Łukasz Pawłowski, Aleksandra Mielewczyk-Gryń, Gabriel Strugała, Krzysztof Rokosz, Sofia Gaiaschi, Patrick Chapon, Steinar Raaen and Andrzej Zieliński
Materials 2021, 14(7), 1638; https://0-doi-org.brum.beds.ac.uk/10.3390/ma14071638 - 26 Mar 2021
Cited by 6 | Viewed by 1545
Abstract
In this work, nanohydroxyapatite coatings with nanosilver and nanocopper have been fabricated and studied. The presented results concern coatings with a chemical composition that has never been proposed before. The present research aims to characterize the effects of nanosilver and nanocopper, dispersed in [...] Read more.
In this work, nanohydroxyapatite coatings with nanosilver and nanocopper have been fabricated and studied. The presented results concern coatings with a chemical composition that has never been proposed before. The present research aims to characterize the effects of nanosilver and nanocopper, dispersed in nanohydroxyapatite coatings and deposited on a new, non-toxic Ti13Zr13Nb alloy, on the physical and mechanical properties of coatings. The coatings were obtained by a one-stage electrophoretic process. The surface topography, and the chemical and phase compositions of coatings were examined with scanning electron microscopy, atomic force microscopy, X-ray diffractometry, glow discharge optical emission spectroscopy, and energy-dispersive X-ray spectroscopy. The mechanical properties of coatings were determined by nanoindentation tests, while coatings adhesion was determined by nanoscratch tests. The results demonstrate that copper addition increases the hardness and adhesion. The presence of nanosilver has no significant influence on the adhesion of coatings. Full article
(This article belongs to the Special Issue Micro- and Nanoparticles in Biomedical and Cosmetic Applications)
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17 pages, 26635 KiB  
Article
Lyophilized Emulsions in the Form of 3D Porous Matrices as a Novel Material for Topical Application
by Weronika Prus-Walendziak and Justyna Kozlowska
Materials 2021, 14(4), 950; https://0-doi-org.brum.beds.ac.uk/10.3390/ma14040950 - 17 Feb 2021
Cited by 6 | Viewed by 3053
Abstract
Researchers are constantly searching for innovations that can be applied to the cosmetic industry. Production of porous materials stored in a lyophilized form and swollen directly before use may be beneficial considering their facilitated packaging, transport and storage. In this study, we propose [...] Read more.
Researchers are constantly searching for innovations that can be applied to the cosmetic industry. Production of porous materials stored in a lyophilized form and swollen directly before use may be beneficial considering their facilitated packaging, transport and storage. In this study, we propose porous materials based on sodium alginate, gelatin, glycerol and lipids (cottonseed oil and beeswax) obtained by freeze-drying and cross-linking. Material composition with the most promising properties was modified by the addition of PLA microparticles with Calendula officinalis flower extract. The structure and properties of obtained porous materials were analyzed. ATR-FTIR, mechanical properties, residual moisture content, porosity and density were assessed, as well as swelling properties and degradation after their cross-linking. The loading capacity and in vitro release of Calendula officinalis flower extract were performed for samples with incorporated PLA microparticles containing plant extract. The modification of the composition and fabrication method of materials significantly influenced their physicochemical properties. The selected plant extract was successfully incorporated into polymeric microparticles that were subsequently added into developed materials. Prepared materials may be considered during designing new cosmetic formulations. Full article
(This article belongs to the Special Issue Micro- and Nanoparticles in Biomedical and Cosmetic Applications)
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20 pages, 4180 KiB  
Article
Design of Sodium Alginate/Gelatin-Based Emulsion Film Fused with Polylactide Microparticles Charged with Plant Extract
by Weronika Prus-Walendziak and Justyna Kozlowska
Materials 2021, 14(4), 745; https://0-doi-org.brum.beds.ac.uk/10.3390/ma14040745 - 05 Feb 2021
Cited by 13 | Viewed by 3629
Abstract
This study aimed at designing emulsion films based on sodium alginate, gelatin, and glycerol, and their modification by the addition of lipids (cottonseed oil and beeswax). Film composition with the most promising properties was further modified by the incorporation of polylactide (PLA) microparticles [...] Read more.
This study aimed at designing emulsion films based on sodium alginate, gelatin, and glycerol, and their modification by the addition of lipids (cottonseed oil and beeswax). Film composition with the most promising properties was further modified by the incorporation of polylactide (PLA) microparticles with Calendula officinalis flower extract. PLA microspheres were obtained by the emulsion/solvent evaporation method. The size distribution of oily particles in emulsions was investigated. Mechanical properties, moisture content, UV-Vis spectra, and the color of films were analyzed, while biophysical skin parameters were assessed after their application to the skin. Moreover, the contact angles were measured, and the surface free energy of polymeric films was determined. An investigation of the amount of Calendula officinalis flower extract which can be incorporated into PLA microparticles was performed. The modification of the composition of films significantly influenced their physicochemical properties. The selected active ingredient in the form of plant extract was successfully incorporated into polymeric microparticles that were further added into the developed emulsion film. The condition of the skin after the application of obtained emulsion films improved. The prepared materials, especially containing microparticles with plant extract, can be considered for designing new cosmetic forms, such as cosmetic masks, as well as new topical formulations for pharmaceutical delivery. Full article
(This article belongs to the Special Issue Micro- and Nanoparticles in Biomedical and Cosmetic Applications)
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