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Leveraging Advancements in Nanomaterials: Metrology, Synthesis and Properties for Biomedical Applications

A special issue of Materials (ISSN 1996-1944). This special issue belongs to the section "Advanced Nanomaterials and Nanotechnology".

Deadline for manuscript submissions: closed (20 September 2022) | Viewed by 6602

Special Issue Editor


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Guest Editor
Biophotonics Centre, Prokhorov General Physics Institute, Russian Academy of Sciences, Moscow, Russia
Interests: nanoparticles synthesis; nanoparticles metrology; laser ablation; interaction of laser radiation with matter

Special Issue Information

Dear Colleagues,

Let me present to your attention the Special Issue on "Leveraging Advancements in Nanomaterials: Metrology, Synthesis and Properties for Biomedical Applications". To participate in this special issue, I invite all researchers and researchers involved in the nanoworld. In a special issue, all issues related to the nanoworld, from production and metrology, to application in real sectors of the economy, will be considered. Review articles are welcomed, as well as articles devoted to the prospects for the development of this field of science in the future. The main topics of the special edition are listed below. these topics are set rather as guidelines for the authors, and not rigidly set postulates.

  • Methods for obtaining nanomaterials (laser ablation, explosion, all types of chemical synthesis, "green" synthesis, etc.)
  • Methods for obtaining nanostructured materials (laser ablation, mechanical structuring methods, etching, chemical structuring methods, etc.)
  • Methods for assessing the physical properties of nanomaterials and composite materials based on them (any physical or chemical methods of analysis)
  • Laser and optical technologies for the study of nanomaterials (all types of microscopy, spectroscopy, luminescence analysis, fluorometry, scatterometry, etc.)
  • Metrology of nanomaterials (any physical or chemical methods of analysis)
  • Biomedical application of nanomaterials or materials based on them (targeted delivery, controlled release, improvement of the properties of medical materials, new composite materials, materials for prosthetics, etc.) Application of nanomaterials in the food industry and agriculture (nanoscale fertilizers, nanoscale sensors, technologies for greenhouses, technologies for veterinary medicine and agronomy, packaging materials with special properties, antibacterial and biosafety materials).

Dr. Aleksander V. Simakin
Guest Editor

Manuscript Submission Information

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Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Materials is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • methods for obtaining nanomaterials
  • methods for obtaining nanostructured materials
  • methods for assessing the physical properties of nanomaterials
  • laser and optical technologies for the study of nanomaterials
  • metrology of nanomaterials
  • biomedical applications of nanomaterials
  • application of nanomaterials in the food industry and agriculture

Published Papers (3 papers)

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Research

18 pages, 4821 KiB  
Article
Synthesis of a Novel, Biocompatible and Bacteriostatic Borosiloxane Composition with Silver Oxide Nanoparticles
by Denis N. Chausov, Veronika V. Smirnova, Dmitriy E. Burmistrov, Ruslan M. Sarimov, Alexander D. Kurilov, Maxim E. Astashev, Oleg V. Uvarov, Mikhail V. Dubinin, Valery A. Kozlov, Maria V. Vedunova, Maksim B. Rebezov, Anastasia A. Semenova, Andrey B. Lisitsyn and Sergey V. Gudkov
Materials 2022, 15(2), 527; https://0-doi-org.brum.beds.ac.uk/10.3390/ma15020527 - 11 Jan 2022
Cited by 11 | Viewed by 1928
Abstract
Microbial antibiotic resistance is an important global world health problem. Recently, an interest in nanoparticles (NPs) of silver oxides as compounds with antibacterial potential has significantly increased. From a practical point of view, composites of silver oxide NPs and biocompatible material are of [...] Read more.
Microbial antibiotic resistance is an important global world health problem. Recently, an interest in nanoparticles (NPs) of silver oxides as compounds with antibacterial potential has significantly increased. From a practical point of view, composites of silver oxide NPs and biocompatible material are of interest. A borosiloxane (BS) can be used as one such material. A composite material combining BS and silver oxide NPs has been synthesized. Composites containing BS have adjustable viscoelastic properties. The silver oxide NPs synthesized by laser ablation have a size of ~65 nm (half-width 60 nm) and an elemental composition of Ag2O. The synthesized material exhibits strong bacteriostatic properties against E. coli at a concentration of nanoparticles of silver oxide more than 0.01%. The bacteriostatic effect depends on the silver oxide NPs concentration in the matrix. The BS/silver oxide NPs have no cytotoxic effect on a eukaryotic cell culture when the concentration of nanoparticles of silver oxide is less than 0.1%. The use of the resulting composite based on BS and silver oxide NPs as a reusable dry disinfectant is due to its low toxicity and bacteriostatic activity and its characteristics are not inferior to the medical alloy nitinol. Full article
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18 pages, 3464 KiB  
Article
A Novel Biodegradable Composite Polymer Material Based on PLGA and Silver Oxide Nanoparticles with Unique Physicochemical Properties and Biocompatibility with Mammalian Cells
by Veronika V. Smirnova, Denis N. Chausov, Dmitriy A. Serov, Valery A. Kozlov, Petr I. Ivashkin, Roman Y. Pishchalnikov, Oleg V. Uvarov, Maria V. Vedunova, Anastasia A. Semenova, Andrey B. Lisitsyn and Alexander V. Simakin
Materials 2021, 14(22), 6915; https://0-doi-org.brum.beds.ac.uk/10.3390/ma14226915 - 16 Nov 2021
Cited by 14 | Viewed by 2471
Abstract
A method for obtaining a stable colloidal solution of silver oxide nanoparticles has been developed using laser ablation. The method allows one to obtain nanoparticles with a monomodal size distribution and a concentration of more than 108 nanoparticles per mL. On the [...] Read more.
A method for obtaining a stable colloidal solution of silver oxide nanoparticles has been developed using laser ablation. The method allows one to obtain nanoparticles with a monomodal size distribution and a concentration of more than 108 nanoparticles per mL. On the basis of the obtained nanoparticles and the PLGA polymer, a nanocomposite material was manufactured. The manufacturing technology allows one to obtain a nanocomposite material without significant defects. Nanoparticles are not evenly distributed in the material and form domains in the composite. Reactive oxygen species (hydrogen peroxide and hydroxyl radical) are intensively generated on the surfaces of the nanocomposite. Additionally, on the surface of the composite material, an intensive formation of protein long-lived active forms is observed. The ELISA method was used to demonstrate the generation of 8-oxoguanine in DNA on the developed nanocomposite material. It was found that the multiplication of microorganisms on the developed nanocomposite material is significantly decreased. At the same time, the nanocomposite does not inhibit proliferation of mammalian cells. The developed nanocomposite material can be used as an affordable and non-toxic nanomaterial to create bacteriostatic coatings that are safe for humans. Full article
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18 pages, 69191 KiB  
Article
Additive Production of a Material Based on an Acrylic Polymer with a Nanoscale Layer of Zno Nanorods Deposited Using a Direct Current Magnetron Discharge: Morphology, Photoconversion Properties, and Biosafety
by Dmitry E. Burmistrov, Denis V. Yanykin, Mark O. Paskhin, Egor V. Nagaev, Alexey D. Efimov, Andrey V. Kaziev, Dmitry G. Ageychenkov and Sergey V. Gudkov
Materials 2021, 14(21), 6586; https://0-doi-org.brum.beds.ac.uk/10.3390/ma14216586 - 02 Nov 2021
Cited by 9 | Viewed by 1713
Abstract
On the basis of a direct current magnetron, a technology has been developed for producing nanoscale-oriented nanorods from zinc oxide on an acrylic polymer. The technology makes it possible to achieve different filling of the surface with zinc oxide nanorods. The nanorods is [...] Read more.
On the basis of a direct current magnetron, a technology has been developed for producing nanoscale-oriented nanorods from zinc oxide on an acrylic polymer. The technology makes it possible to achieve different filling of the surface with zinc oxide nanorods. The nanorods is partially fused into the polymer; the cross section of the nanorods is rather close to an elongated ellipse. It is shown that, with intense abrasion, no delamination of the nanorods from the acrylic polymer is observed. The zinc oxide nanorods abrades together with the acrylic polymer. Zinc oxide nanorods luminesces with the wavelength most preferable for the process of photosynthesis in higher plants. It was shown that plants grown under the obtained material grow faster and gain biomass faster than the control group. In addition, it was found that on surfaces containing zinc oxide nanorods, a more intense formation of such reactive oxygen species as hydrogen peroxide and hydroxyl radical is observed. Intensive formation of long-lived, active forms of the protein is observed on the zinc oxide coating. The formation of 8-oxoguanine in DNA in vitro on a zinc oxide coating was shown using ELISA method. It was found that the multiplication of microorganisms on the developed material is significantly hampered. At the same time, eukaryotic cells of animals grow and develop without hindrance. Thus, the material we have obtained can be used in photonics (photoconversion material for greenhouses, housings for LEDs), and it is also an affordable and non-toxic nanomaterial for creating antibacterial coatings. Full article
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