Special Issue "Celiac Disease and Non-celiac Gluten Sensitivity"
Deadline for manuscript submissions: closed (10 April 2021).
Interests: celiac disease; gluten intolerance; Helicobacter pylori; gastrointestinal tumors; liver diseases
Special Issues, Collections and Topics in MDPI journals
Celiac disease (CD) is a gluten-induced immune-mediated enteropathy, characterized by the presence of specific serum autoantibodies and genetic markers. Although the inflammatory process specifically targets the intestinal mucosa, patients may present with gastrointestinal and/or extraintestinal signs or symptoms,, suggesting that CD is an autoimmune systemic disease.
Non-Celiac gluten sensitivity (NCGS) is diagnosed in individuals who do not have CD or wheat allergy (WA), but who have intestinal and/or extraintestinal symptoms related to ingestion of gluten-containing grains, with symptomatic improvement on their withdrawal. The clinical variability and the lack of validated biomarkers for NCGS, make establishing the prevalence, reaching a diagnosis, and further study of this condition difficult.
Nevertheless, it is possible to differentiate specific gluten-related disorders from other conditions based on currently available investigations and algorithms. Clinicians cannot distinguish between Celiac disease and Non-Celiac gluten sensitivity by symptoms, as they are similar in both. Therefore, screening for CD must occur before a gluten-free diet (GFD) is implemented, since once a patient initiates this diet, testing for CD is no longer accurate.
It is useful to recall that the prevalence of gluten-related disorders is rising, and that many individuals are empirically trying a GFD, for a variety of signs and symptoms.
Prof. Luis Rodrigo
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
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Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1800 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- Celiac disease/diagnosis
- Celiac disease/immunology
- Celiac disease/differential diagnosis
- Celiac disease/treatment/evolution
- Non-Celiac gluten sensitivity/diagnosis
- Non-Celiac gluten sensitivity/immunology
- Non-Celiac gluten sensitivity/differential diagnosis
- Non-Celiac gluten sensitivity/treatment/evolution