Share This Special Issue

Special Issue Editor

Dr. Tiziana Filardi

E-Mail Website
Guest Editor

Department of Experimental Medicine, "Sapienza" University of Rome, 00185 Rome, Italy
Interests: endocrinology; metabolic diseases; type 2 diabetes; type 1 diabetes; gestational diabetes

Special Issue Information

Dear Colleagues,

The prevalence of gestational diabetes has significantly increased over the last few years, in line with the dramatic rise in obesity and type 2 diabetes. This condition significantly impacts maternal and fetal health, leading to short-term and long-term adverse outcomes for both mothers and their offspring.

The purpose of this Special Issue is to discuss different aspects of gestational diabetes, which might help to strengthen prevention and treatment strategies. Specifically, the role of emerging risk factors and novel biomarkers with potential diagnostic and prognostic utility will be examined, as well as the impact of both well-established and new therapeutic strategies on short- and long-term clinical outcomes of pregnancy complicated by gestational diabetes. Furthermore, developments in the understanding of the pathophysiological aspects of this condition will also be explored. Research articles, review articles, as well as short communications are invited.

Dr. Tiziana Filardi
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Medicina is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1800 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

gestational diabetes risk
gestational diabetes prevention
gestational diabetes pathophysiology
novel diagnostic biomarkers for gestational diabetes
treatment strategies for gestational diabetes
maternal outcomes of gestational diabetes
fetal outcomes of gestational diabetes
long-term complications of gestational diabetes

Published Papers (2 papers)

Download All Papers

Research

Jump to: Review

12 pages, 1112 KiB

Open AccessArticle

Prognostic Gene Predictors of Gestational Diabetes in Endometrium and Follicular Fluid of Women after Infertility

by Brigita Vaigauskaitė, Raminta Baušytė, Elvina Valatkaitė, Giedrė Skliutė, Edita Kazėnaitė, Diana Ramašauskaitė and Rūta Navakauskienė

Medicina 2022, 58(4), 498; https://0-doi-org.brum.beds.ac.uk/10.3390/medicina58040498 - 30 Mar 2022

Cited by 1 | Viewed by 2018

Abstract

Background and objectives. Gestational diabetes mellitus is an increasingly diagnosed metabolic disorder during pregnancy with unknown pathological pathways. Taking into account the growing numbers of women who are conceiving after assisted reproductive technologies, they comprise an engaging target group for gestational diabetes mellitus etiopathogenesis research. In terms of metabolism and genetics, as the evidence shows, both unexplained infertility and gestational diabetes mellitus pose challenges for their interpretation due to the complex bodily processes. Materials and Methods. Our study examined the expression of genes (IGF2, GRB10, CRTC2, HMGA2, ESR1, DLK1, SLC6A15, GPT2, PLAGL1) associated with glucose metabolism in unexplained infertility patients who conceived after in vitro fertilization procedure, were diagnosed with GDM and their findings were compared with control population. Results. There were no significant differences in gene expression of endometrium stromal cells between healthy pregnant women and women with gestational diabetes, although the significant downregulation of CRTC2 was observed in the follicular fluid of women with gestational diabetes mellitus. Moreover, expression of HMGA2 and ESR1 was significantly reduced in FF cells when compared to endometrial cells. Conclusions. These findings may indicate about the importance of follicular fluid as an indicator for gestational diabetes and should be explored more by further research. Full article

(This article belongs to the Special Issue Prevention and Treatment of Gestational Diabetes)

► Show Figures

Figure 1

Review

Jump to: Research

14 pages, 452 KiB

Open AccessReview

Negotiating Gestational Diabetes Mellitus in India: A National Approach

by Uday Thanawala, Hema Divakar, Rajesh Jain and Mukesh M. Agarwal

Medicina 2021, 57(9), 942; https://0-doi-org.brum.beds.ac.uk/10.3390/medicina57090942 - 06 Sep 2021

Cited by 7 | Viewed by 4389

Abstract

The worldwide epidemic of diabetes mellitus and hyperglycemia in pregnancy (HIP) presents many challenges, some of which are country-specific. To address these specific problems, parochial resolutions are essential. In India, the government, by working in tandem with (a) national groups such as the Diabetes in Pregnancy Study Group of India, and (b) global organizations such as the International Diabetes Federation, has empowered the medical and paramedical staff throughout the country to manage HIP. Additionally, despite their academic university backgrounds, Indian health planners have provided practical guidelines for caregivers at the ground level, who look up to these experts for guidance. This multipronged process has helped to negotiate some of the multiple problems that are indigenous and exclusive to India. This review traces the Indian journey to manage and prevent HIP with simple, constructive, and pragmatic solutions. Full article

(This article belongs to the Special Issue Prevention and Treatment of Gestational Diabetes)

► Show Figures