New Perspectives in Laparoscopic Liver Resection

A special issue of Medicina (ISSN 1648-9144).

Deadline for manuscript submissions: closed (30 June 2022) | Viewed by 3636

Special Issue Editor


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Guest Editor
Department of Surgery, Seoul National University Bundang Hospital, Seongnam 13620, Republic of Korea
Interests: liver transplantation; liver surgery; hepatocellular carcinoma; minimal invasive surgery
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Special Issue Information

Dear Colleagues,

Laparoscopic liver resection has been rapidly developed and propagated. Many reports about short-term outcome and oncologic benefit of laparoscopic liver resection for malignant tumors have been published. However, laparoscopic liver resection has not been accepted for standard treatment of hepatectomy because of surgical difficulty and reproducibility. In this Special Issue, we will invite evidences, technical improvement, and expert perspectives of laparoscopic liver resection.

Prof. Dr. Jai Young Cho
Guest Editor

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Keywords

  • laparoscopic hepatectomy
  • minimal invasive liver resection
  • hepatocellular carcinoma
  • technique
  • prognosis
  • complication

Published Papers (2 papers)

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Research

9 pages, 488 KiB  
Article
Long-Term Outcomes of Laparoscopic Liver Resection for Centrally Located Hepatocellular Carcinoma
by Hyo Jun Kim, Jai Young Cho, Ho-Seong Han, Yoo-Seok Yoon, Hae Won Lee, Jun Suh Lee, Boram Lee, Yeongsoo Jo, Meeyouong Kang, Yeshong Park and Eunhye Lee
Medicina 2022, 58(6), 737; https://0-doi-org.brum.beds.ac.uk/10.3390/medicina58060737 - 30 May 2022
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Abstract
Background and Objectives: The feasibility of laparoscopic liver resection (LLR) for centrally located hepatocellular carcinoma (cHCC 1 cm of the hilum, major hepatic veins, and inferior vena cava) is still controversial. This study aims to evaluate the feasibility and safety of LLR for [...] Read more.
Background and Objectives: The feasibility of laparoscopic liver resection (LLR) for centrally located hepatocellular carcinoma (cHCC 1 cm of the hilum, major hepatic veins, and inferior vena cava) is still controversial. This study aims to evaluate the feasibility and safety of LLR for cHCC and compare the perioperative outcomes with those of open liver resection (OLR). Materials and Methods: This retrospective study included 110 patients who underwent LLR (n = 59) or open liver resection (OLR) (n = 51) for cHCC between January 2004 and September 2018. LLR group was divided into the following two subgroups according to the date of operation: Group 1 (n = 19) and Group 2 (n = 40), to account for the advancement in the laparoscopic techniques. Results: No mortality within 3 months was observed. There were no significant differences in operation time (285 vs. 280 min; p = 0.938) and postoperative complication rate (22.0% vs. 27.5%; p = 0.510) between both groups. However, intraoperative blood loss (500 vs. 700 mL; p < 0.001), transfusion rate (10.2% vs. 31.4%; p = 0.006), and hospital stay (6 vs. 10 days; p < 0.001) were significantly lower in the LLR group than in the OLR group. In the LLR group, Group 2, showed a shorter hospital stay than Group 1 (6 vs. 8 days; p = 0.006). There were improvements in the operation time (280 vs. 360 min; p = 0.036) and less intraoperative blood loss (455 vs. 500 mL; p = 0.075) in Group 2. Conclusions: We demonstrated that LLR can be safely performed in highly selected patients with cHCC. Full article
(This article belongs to the Special Issue New Perspectives in Laparoscopic Liver Resection)
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9 pages, 666 KiB  
Article
A Case-Matched Analysis of Laparoscopic Liver Resection for Hepatocellular Carcinoma Located in Posterosuperior Segments of the Liver According to Adaption of Developed Techniques
by Yujin Kwon, Boram Lee, Jai Young Cho, Ho-Seong Han, Yoo-Seok Yoon, Hae Won Lee, Jun Suh Lee, Munwhan Kim and Youngsoo Jo
Medicina 2022, 58(4), 543; https://0-doi-org.brum.beds.ac.uk/10.3390/medicina58040543 - 14 Apr 2022
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Abstract
Background and Objectives: Laparoscopic liver resection (LLR) for the hepatocellular carcinoma (HCC) located in posterosuperior (PS) segment is technically demanding, but has been overcome by accumulated experiences and technological improvements. We analyzed peri-and post-operative results before and after the adaptation of the [...] Read more.
Background and Objectives: Laparoscopic liver resection (LLR) for the hepatocellular carcinoma (HCC) located in posterosuperior (PS) segment is technically demanding, but has been overcome by accumulated experiences and technological improvements. We analyzed peri-and post-operative results before and after the adaptation of the enhanced techniques. Materials and Methods: We retrospectively reviewed 246 patients who underwent LLR for HCC in PS segments from September 2003 to December 2019. According to the introduction of advanced techniques including intercostal trocars, Pringle maneuver, and semi-lateral French position, the patients were divided into Group 1 (n = 43), who underwent LLR from September 2003 to December 2011, and Group 2 (n = 203), who underwent LLR from January 2012 to December 2019. Among these cases, 136 patients (Group 1 = 34, Group 2 = 102) were selected by case-matched analysis using perioperative variables. Results: Mean operation time (362 min vs. 291 min) and hospital stay (11 days vs. 8 days, p = 0.023) were significantly longer in Group 1 than Group 2. Otherwise, disease-free survival (DFS) rate was shorter and resection margin (1.3 mm vs. 0.7 mm, p = 0.034) were smaller in Group 2 than Group 1. However, there was no difference in type of complication (p = 0.084), severity of complication graded by the Clavien–Dindo grade system (p = 0.394), and 5-year overall survival (OS) rates (p = 0.986). In case-matched analysis, operation time (359 min vs. 266 min p = 0.002) and hospital stay (11.5 days vs. 8.0 days, p = 0.032) were significantly different, but there was no significant difference in resection margin, DFS, and OS. Conclusions: The adaptation of improved techniques has reduced the complexity of LLR in PS segments. Full article
(This article belongs to the Special Issue New Perspectives in Laparoscopic Liver Resection)
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