Treatment and Management of Lower Gastrointestinal Disorders

A special issue of Medicina (ISSN 1648-9144).

Deadline for manuscript submissions: closed (30 September 2021) | Viewed by 6026

Special Issue Editor


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Guest Editor
Department of Gastroenterology, University of Timisoara, Timisoara, Romania
Interests: lower gastrointestinal disorders; colorectal neoplasia; inflammatory bowel diseases; functional bowel disorders; anorectal disorders; management; predictive biomarkers; targeted therapies

Special Issue Information

Dear Colleagues,

In this Special Issue of Medicina entitled “Treatment and Management of Lower Gastrointestinal Disorders” we aim to approach the most recent advances in this field, which includes a large spectrum of diseases such as colon polyps and colorectal cancer, inflammatory bowel diseases (IBDs), colitis, intestinal pseudo-obstruction, angiodysplastic and diverticular disease, bowel incontinence, chronic diarrhea/constipation, irritable bowel syndrome (IBS), and other functional bowel and anorectal diseases, hemorrhoids, anal fissures and fistulas, perianal abscesses, and others. We especially aim to address innovative treatment strategies and novel predictive markers of prognosis and treatment response. These are emerging fields developed with the goal of achieving personalized management, associated with best quality of life and prognosis of patients. There are still numerous issues that need to be elucidated:

- Which are the modern strategies for the management of colon polyps and the most suitable modern endoscopic resection techniques?

- Which are the best prognostic biomarkers for colorectal cancer and novel therapeutic perspectives?

- What does the future management of IBD look like? Which are the most efficient predictive markers of prognosis and treatment response, and how could they influence management towards a personalized approach?

- Which are the modern approaches to treat functional disorders?

- Which is the best treatment and prophylaxis of diverticulitis?

- Is the treatment of anorectal disorders entering a new era?

This Issue will aim to answer to these and other questions regarding the management of lower gastrointestinal disorders.

Dr. Adrian Goldiş
Guest Editor

Manuscript Submission Information

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Keywords

  • lower gastrointestinal disorders
  • colorectal neoplasia
  • inflammatory bowel diseases
  • functional bowel disorders
  • anorectal disorders
  • management
  • predictive biomarkers
  • targeted therapies

Published Papers (1 paper)

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8 pages, 8773 KiB  
Case Report
Anal Canal Duplication in an Adult Female—Case Report and Pathology Guiding
by Tudor Mateescu, Cristi Tarta, Paul Stanciu, Alis Dema and Fulger Lazar
Medicina 2021, 57(11), 1205; https://0-doi-org.brum.beds.ac.uk/10.3390/medicina57111205 - 04 Nov 2021
Cited by 3 | Viewed by 5526
Abstract
Anal canal duplication (ACD) is a very rare condition, diagnosed and treated mostly in childhood. Less than 90 cases have been reported in the literature so far. We are presenting a case of a young woman who underwent surgical excision of the duplication [...] Read more.
Anal canal duplication (ACD) is a very rare condition, diagnosed and treated mostly in childhood. Less than 90 cases have been reported in the literature so far. We are presenting a case of a young woman who underwent surgical excision of the duplication when she was 27 years old. The patient was unaware of her condition and was referred from a gynaecological office to the surgical department with a history of perianal discomfort and mucus discharge. Local examination showed an external orifice posterior to the anal opening, on the median line, which had the macroscopic appearance of a secondary anal orifice. The opening was about 0.5 cm in diameter. Exploration of the tract revealed a length of about 4 cm. MRI described the aforementioned tract, parallel to the anal canal, with no other anomalies mentioned. Under spinal anesthesia, with the patient in jackknife position, the accessory anal canal was surgically excised. The pathology report showed the presence of smooth muscle fibers and typical anal glands in the specimen. After a five-year follow-up, the patient showed no recurrence or any other related local symptoms. Absence of perianal abscess from the patient history, along with the macroscopic aspect of the opening similar to a secondary anal orifice on the midline, should raise the suspicion of ACD. Due to the lack of bothersome symptomatology, the patient did not seek any special investigations for her condition until she was in her late twenties. ACD is a very rare condition in adults that might pass unnoticed, but a midline opening posterior to the anus should always raise the suspicion of a secondary anal canal. Surgery is the only cure for this condition with good results after a proper pre-operative workout to reveal others simultaneous malformations. Full article
(This article belongs to the Special Issue Treatment and Management of Lower Gastrointestinal Disorders)
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