Membrane Domains on Protein-Lipid Interaction

Dear Colleagues,

Our knowledge on biological membranes has substantially changed over the past several years, from the fluid mosaic idea to the current concept of lipids and proteins separating into microdomains that differ in their protein and lipid compositions. The role of lipids and membrane proteins is not limited to constituting the cell barrier. They are also involved in a wide range of processes including intracellular and extracellular transport, communication, cell migration, forming cell shape and participation in the mechanisms of signal transduction that regulate cell function and homeostasis. Investigation of the world of membrane domains and the function of specific protein-lipid complexes has become possible thanks to the novel advanced tools used to study functions of diverse lipid classes in membranes with structural analysis and simulations at the atomic resolution. This Special Issue will highlight the importance of the membrane domains on protein-lipid interactions and its implications for our understanding of the overall organization and functioning of cell membranes and its relation to myriad cellular outcomes. We seek submissions of experimental and computational approaches concentrated on protein-lipid interactions on molecular and membrane levels. The reviews on promising methods or techniques to study membrane organization and molecular interactions are also highly welcome.

Dr. Agnieszka Polit
Dr. Paweł Mystek
Guest Editors

Manuscript Submission Information

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Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Membranes is an international peer-reviewed open access monthly journal published by MDPI.

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• biological membranes
• lipid domains
• membrane organization
• model membranes
• lipid-protein interactions
• lipid rafts
• molecular recognition
• membrane regulation of signal transduction
• membrane protein clustering
• protein-enriched domains
• membrane protein diffusion
• membrane domain targeting
• plasma membrane compartmentalization
• molecular dynamics simulation
• lipid binding motifs