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Metabolites
Special Issues
Cardiometabolic Effect of the Mediterranean Diet
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Cardiometabolic Effect of the Mediterranean Diet

A special issue of Metabolites (ISSN 2218-1989). This special issue belongs to the section "Nutrition and Metabolism".

Deadline for manuscript submissions: closed (15 July 2022) | Viewed by 4531

Special Issue Editors

Dr. Evangeline Mantzioris

E-Mail Website
Guest Editor
Clinical and Health Sciences & Alliance for Research in Exercise, Nutrition and Activity (ARENA) University of South Australia, Adelaide, SA 5001, Australia
Interests: Mediterranean diets; fatty acids; n-3 fatty acids; sports nutrition; inflammation; inflammatory-based diseases
Dr. Anthony Villani

E-Mail Website
Guest Editor
School of Health and Behavioural Sciences, University of the Sunshine Coast, Sippy Downs, QLD 4556, Australia
Interests: mediterranean diet to support healthy ageing; sarcopenia; frailty; physical function; nutrition and type 2 diabetes
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

The Mediterranean diet (MedDiet) is commonly recognized as a health-promoting dietary pattern due to its familiar characteristics, including the regular consumption of vegetables, fruits, nuts, legumes, unprocessed cereals, and extra-virgin olive oil.

Adherence to a MedDiet affords protection from insulin resistance-related cardiometabolic conditions, including type 2 diabetes (T2DM) and cardiovascular disease, and is inversely associated with central obesity in both epidemiological studies and dietary intervention studies. These benefits are also independent of caloric restriction and weight loss due to the large number of functional foods and nutraceuticals present within the dietary pattern. Being predominately plant-based, the MedDiet is naturally low in saturated fat and rich in several functional components, including vitamins and minerals, carotenoids, unsaturated fatty acids, and phenolic compounds. These components of the MedDiet have antioxidant and anti-inflammatory properties which are involved in preventing and ameliorating the pathophysiology involved in numerous cardiometabolic disorders.

We therefore invite manuscripts for this Special Issue describing epidemiological, interventional and implementation studies which explore the potential efficacy of MedDiet adherence on cardiometabolic health in all populations of health and disease.

Dr. Evangeline Mantzioris
Dr. Anthony Villani
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Metabolites is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • Mediterranean diet
  • human metabolism
  • cardiovascular health
  • metabolic health
  • obesity
  • weight loss
  • biomarkers
  • experimental studies
  • epidemiological studies

Published Papers (1 paper)

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18 pages, 1076 KiB  
Protocol
Efficacy, Feasibility and Acceptability of a Mediterranean Diet Intervention on Hormonal, Metabolic and Anthropometric Measures in Overweight and Obese Women with Polycystic Ovary Syndrome: Study Protocol
by Nicole Scannell, Lisa Moran, Evangeline Mantzioris, Stephanie Cowan and Anthony Villani
Metabolites 2022, 12(4), 311; https://0-doi-org.brum.beds.ac.uk/10.3390/metabo12040311 - 31 Mar 2022
Cited by 4 | Viewed by 4071
Abstract
Polycystic ovary syndrome (PCOS) is a common endocrine condition in reproductive-aged women associated with metabolic, reproductive and psychological features. Lifestyle modification (diet/physical activity) is considered first-line treatment for PCOS. However, there is limited high-quality evidence to support therapeutic dietary interventions for PCOS beyond [...] Read more.
Polycystic ovary syndrome (PCOS) is a common endocrine condition in reproductive-aged women associated with metabolic, reproductive and psychological features. Lifestyle modification (diet/physical activity) is considered first-line treatment for PCOS. However, there is limited high-quality evidence to support therapeutic dietary interventions for PCOS beyond general population-based healthy eating guidelines. Adherence to a Mediterranean diet (MedDiet), with or without energy restriction, improves cardiometabolic health in populations including persons with or at high risk of cardiovascular disease and type 2 diabetes. However, there is limited research examining the MedDiet in PCOS. Therefore, this 12 week randomized controlled trial will investigate the efficacy of a MedDiet on cardiometabolic and hormonal parameters and explore its acceptability and feasibility in PCOS. Forty-two overweight and obese women with PCOS (aged 18–45 years) will be randomized to receive dietary advice consistent with Australian Dietary Guidelines or an ad libitum MedDiet intervention. All participants will receive fortnightly counselling to facilitate behaviour change. The primary outcomes will be changes in insulin resistance, glucose, total testosterone and sex hormone-binding globulin. Secondary outcomes include changes in body weight and feasibility and acceptability of the MedDiet intervention. The results of this study will provide further evidence on specific dietary approaches for management of PCOS. Full article
(This article belongs to the Special Issue Cardiometabolic Effect of the Mediterranean Diet)
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