Parasite Metabolism-Quirks, Drug Targets, Inhibition, Mode of Action Studies

A special issue of Metabolites (ISSN 2218-1989). This special issue belongs to the section "Integrative Metabolomics".

Deadline for manuscript submissions: closed (1 March 2022) | Viewed by 350

Special Issue Editors

School of Biology, University of St Andrews, St Andrews, UK
Interests: biosynthesis and uptake of phospholipids in protozoan parasites; the enzymology of biosynthetic enzymes in parasites; lipidomics and focussed metabolomics of pathogens; “simple” chemistry towards drugs for neglected disease; structure, function & biosynthesis of parasite glycoconjugates including GPI anchors
School of Life Sciences, University of Dundee, Dundee DD1 5EH, UK
Interests: using complementary methodologies in the fields of genomics; chemical proteomics and cell biology to determ
Research Unit UMR5234 (MFP), Université de Bordeauxdisabled, 33076 Bordeaux CEDEX, France
Interests: intermediate and energy metabolism of trypanosomes

Special Issue Information

Dear Colleagues,

The need and desire to understand how a parasite survives and multiplies within a host has to some extent driven the metabolomics field in the last decade, both in terms of technology and its application to gain insightful knowledge.

This knowledge has been invaluable in elucidating biosynthetic pathways and identifying unique and/or essential metabolic steps that allow subsequent validation as drug targets.

This Special Issue (Parasite Metabolism-Quirks, Drug Targets, Inhibition, Mode of Action Studies) is devoted to compiling the latest research in this area.

We therefore invite primary research articles in the generic arena of parasite as well as host–parasite metabolomics; this could include detailed mode of action studies of known or experimental drugs, studies of metabolic fluxes, studies on the identification of novel biosynthetic routes, etc.

We also invite manuscripts on the latest metabolomics methodologies (both acquisitions and data analysis)—an essential part of the cutting-edge understanding of complex biochemical processes.

Other possible areas include the response of the host to the parasitic infection at a metabolic level that could include the identification and validation of biomarkers.

Prof. Dr. Terry K Smith
Dr. Susan Wyllie
Prof. Dr. Frederic Bringaud
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Metabolites is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • parasite metabolism
  • drug targets
  • inhibition
  • mode of action studies
  • labelling
  • methodology
  • quirks

Published Papers

There is no accepted submissions to this special issue at this moment.
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