Feature Papers of Micromachines in Chemistry 2022

A special issue of Micromachines (ISSN 2072-666X). This special issue belongs to the section "C:Chemistry".

Deadline for manuscript submissions: closed (31 December 2022) | Viewed by 4666

Special Issue Editors


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Guest Editor
Department of Biotechnology and Life Science, Tokyo University of Agriculture and Technology (TUAT), 2-24-16 Naka-cho, Koganei-shi, Tokyo 184-8588, Japan
Interests: nanopore; lipid bilayer; microfabrication; electrochemistry; molecular robotics; DNA computing
Special Issues, Collections and Topics in MDPI journals
Nano Bio Integrated System Laboratory, Nagaoka, Niigata 940-2188, Japan
Interests: biorobotics; microfluidics; nanopore sensing
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

We are pleased to announce a new Special Issue entitled “Feature Papers of Micromachines in Chemistry 2022”. In recent years, we have cooperated with some excellent scholars/scientific groups and published several important high-level works, which have already been cited according to the data of Web of Science. We aim to introduce a new insight into science development or cutting-edge technology related to micromachines in the chemistry field, which will make a great contribution to the community.

This Special Issue will be a collection of high-quality papers from excellent scholars around the world. Both original research articles and comprehensive review papers are welcome. The papers will be published, free of charge, with full open access after peer review to benefit both authors and readers.

You are welcome to send short proposals for submissions of Feature Papers to our editorial office ([email protected]) before submission. They will be evaluated by editors at first. Please note that selected full papers will still be subjected to a thorough and rigorous peer review.

We look forward to receiving your excellent work.

Prof. Dr. Ryuji Kawano
Prof. Dr. Kan Shoji
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Micromachines is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

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Published Papers (2 papers)

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Research

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11 pages, 2318 KiB  
Article
Highly Sensitive Electrochemical Endotoxin Sensor Based on Redox Cycling Using an Interdigitated Array Electrode Device
by Kentaro Ito, Kumi Y. Inoue, Takahiro Ito-Sasaki, Miho Ikegawa, Shinichiro Takano, Kosuke Ino and Hitoshi Shiku
Micromachines 2023, 14(2), 327; https://0-doi-org.brum.beds.ac.uk/10.3390/mi14020327 - 27 Jan 2023
Cited by 1 | Viewed by 1290
Abstract
The Limulus amebocyte lysate (LAL) reaction-based assay, the most commonly used endotoxin detection method, requires a skilled technician. In this study, to develop an easy-to-use and highly sensitive endotoxin sensor, we created an electrochemical endotoxin sensor by using an interdigitated array electrode (IDAE) [...] Read more.
The Limulus amebocyte lysate (LAL) reaction-based assay, the most commonly used endotoxin detection method, requires a skilled technician. In this study, to develop an easy-to-use and highly sensitive endotoxin sensor, we created an electrochemical endotoxin sensor by using an interdigitated array electrode (IDAE) device with advantages of amplifiable signals via redox cycling and portability. We added Boc-Leu-Gly-Arg-p-aminophenol (LGR-pAP) as an electrochemical substrate for an LAL reaction and detected p-aminophenol (pAP) released from LGR-pAP as a product of an endotoxin-induced LAL reaction via an IDAE device. The IDAE device showed a great redox cycling efficiency of 79.8%, and a 4.79-fold signal amplification rate. Then, we confirmed that pAP was detectable in the presence of LGR-pAP through chronoamperometry with the potential of the anode stepped from −0.3 to 0.5 V vs. Ag/AgCl while the cathode was biased at −0.3 V vs. Ag/AgCl. Then, we performed an endotoxin assay by using the IDAE device. Our endotoxin sensor detected as low as 0.7 and 1.0 endotoxin unit/L after the LAL reaction for 1 h and 45 min, respectively, and these data were within the cut-off value for ultrapure dialysis fluid. Therefore, our highly sensitive endotoxin sensor is useful for ensuring medical safety. Full article
(This article belongs to the Special Issue Feature Papers of Micromachines in Chemistry 2022)
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Review

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32 pages, 17226 KiB  
Review
Molecular Machines and Microrobots: Nanoarchitectonics Developments and On-Water Performances
by Katsuhiko Ariga
Micromachines 2023, 14(1), 25; https://0-doi-org.brum.beds.ac.uk/10.3390/mi14010025 - 22 Dec 2022
Cited by 8 | Viewed by 2290
Abstract
This review will focus on micromachines and microrobots, which are objects at the micro-level with similar machine functions, as well as nano-level objects such as molecular machines and nanomachines. The paper will initially review recent examples of molecular machines and microrobots that are [...] Read more.
This review will focus on micromachines and microrobots, which are objects at the micro-level with similar machine functions, as well as nano-level objects such as molecular machines and nanomachines. The paper will initially review recent examples of molecular machines and microrobots that are not limited to interfaces, noting the diversity of their functions. Next, examples of molecular machines and micromachines/micro-robots functioning at the air-water interface will be discussed. The behaviors of molecular machines are influenced significantly by the specific characteristics of the air-water interface. By placing molecular machines at the air-water interface, the scientific horizon and depth of molecular machine research will increase dramatically. On the other hand, for microrobotics, more practical and advanced systems have been reported, such as the development of microrobots and microswimmers for environmental remediations and biomedical applications. The research currently being conducted on the surface of water may provide significant basic knowledge for future practical uses of molecular machines and microrobots. Full article
(This article belongs to the Special Issue Feature Papers of Micromachines in Chemistry 2022)
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