Biomaterials and Biomanufacturing

A special issue of Micromachines (ISSN 2072-666X). This special issue belongs to the section "B:Biology and Biomedicine".

Deadline for manuscript submissions: closed (30 October 2021) | Viewed by 3397

Special Issue Editors

Department of Mechanical Engineering, Tsinghua University, Beijing 100084, China
Interests: 3D bioprinting; bioinks; biofabrication; hydrogels; tissue engineering
Department of Mechanical Engineering, Tsinghua University, Beijing 100084, China
Interests: 3D bioprinting; regenerative medicine; additive manufacturing

Special Issue Information

Dear Colleagues,

Biomanufacturing has emerged as a significant approach to engineering in vitro living systems used in diagnostics, therapeutics, and other biomedical applications. Two major enabling technologies for biomanufacturing are bioprinting and bioassembly, both of which apply a “bottom–up” principle to controllably build a living model (e.g., a cellularized tissue construct). Despite the considerable progress in recent years, there remain some enduring challenges, including a lack of biomaterials that facilitate biofunctionality and the interplay between biomaterials and the manufacturing process. Taking 3D bioprinting as an example, there is a great demand for feasible bioinks (a typical example is a cell-laden hydrogel formulation) that could fit into a high-throughput bioprinting process while maintaining embedded cell viability and structural printability.

In this perspective, this Special Issue of Micromachines aims to publish research articles, short communications, and topical reviews focusing on biomanufacturing and the applied biomaterials. Here are some examples of relevant topics:

  • Development and characterization of biomaterials (e.g., polymeric materials, hydrogels, single-cell and cell aggregates, etc.) for biomanufacturing application;
  • Innovation in biomanufacturing technologies (e.g., nozzle-based and vat polymerization-based 3D/4D printing and 3D/4D bioprinting, acoustic manipulation and patterning, self-assembly, bioassembly, and other novel technologies);
  • Application of biomaterials and biomanufacturing (e.g., tissue engineering, drug testing, disease modeling, cancer research, drug delivery, biosensing, biobots/cell bots, and other biorelated applications).

We look forward to receiving your submission of outstanding research outcomes.

Dr. Liliang Ouyang
Prof. Dr. Zhuo Xiong
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Micromachines is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • Biomaterials
  • Biomanufacturing
  • Bioprinting
  • Bioassembly
  • Tissue engineering

Published Papers (1 paper)

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Research

10 pages, 2569 KiB  
Article
Printing a Pacinian Corpuscle: Modeling and Performance
by Kieran Barrett-Snyder, Susan Lane, Nathan Lazarus, W. C. Kirkpatrick Alberts and Brendan Hanrahan
Micromachines 2021, 12(5), 574; https://0-doi-org.brum.beds.ac.uk/10.3390/mi12050574 - 18 May 2021
Cited by 1 | Viewed by 2672
Abstract
The Pacinian corpuscle is a highly sensitive mammalian sensor cell that exhibits a unique band-pass sensitivity to vibrations. The cell achieves this band-pass response through the use of 20 to 70 elastic layers entrapping layers of viscous fluid. This paper develops and explores [...] Read more.
The Pacinian corpuscle is a highly sensitive mammalian sensor cell that exhibits a unique band-pass sensitivity to vibrations. The cell achieves this band-pass response through the use of 20 to 70 elastic layers entrapping layers of viscous fluid. This paper develops and explores a scalable mechanical model of the Pacinian corpuscle and uses the model to predict the response of synthetic corpuscles, which could be the basis for future vibration sensors. The −3dB point of the biological cell is accurately mimicked using the geometries and materials available with off-the-shelf 3D printers. The artificial corpuscles here are constructed using uncured photoresist within structures printed in a commercial stereolithography (SLA) 3D printer, allowing the creation of trapped fluid layers analogous to the biological cell. Multi-layer artificial Pacinian corpuscles are vibration tested over the range of 20–3000 Hz and the response is in good agreement with the model. Full article
(This article belongs to the Special Issue Biomaterials and Biomanufacturing)
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