Micro/Nano Devices for Drug Delivery and Gene Therapy

Dear Colleagues,

Micro- and nanodevices are emerging as novel drug delivery platforms due to their ability for rapid drug transport, high tissue penetration, and precision control. Research is needed on characterization and fabrication of novel nanomaterials for efficient drug delivery. Moreover, the use of novel biomaterials will allow a continuous delivery of drugs at a controlled rate for prolonged periods of time. Advances in autonomous dynamic delivery strategies based on the stimuli-responsive ability will be of interest for therapeutic applications. Micro- and nanodevices, which are also employed with surface treatment, facilitate the binding of sites for genetic materials, and they are particularly used in gene therapy. Different strategies need to be adopted to formulate nanoactuators of biological origin for the transportation of genetic materials from the surface of the cells to intracellular organelles. Fabrication of these nanoactuators by numerate routes involves a self-assembly method, chemical routes, physical treatment of bulk materials, and electrochemistry. Depending on the methodology of fabrication, the utility of the end-product for the purpose of drug and gene delivery is specified. In this Special Issue call, we are looking for potential contributions in the field of micro- and nanomachining for the development of therapeutic devices for drug and gene therapy. Contributions in the section of fabrication procedures, material aspects, and state-of-the-art applications of micro- and nanomachining architecture for gene and drug delivery are anticipated.

Prof. Dr. Kunal Mitra
Dr. Arindam Bit
Guest Editors

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• actuators
• nanotechnology
• smart materials
• therapeutics
• drug delivery