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Micromachines
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Selected Papers from the 3rd International Conference of Microfluidics, Nanofluidics...
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Selected Papers from the 3rd International Conference of Microfluidics, Nanofluidics and Lab-on-a-Chip

A special issue of Micromachines (ISSN 2072-666X).

Deadline for manuscript submissions: closed (31 January 2022) | Viewed by 4216

Special Issue Editors

Prof. Dr. Yonggang Zhu

E-Mail Website
Guest Editor
Center for Microflows and Nanoflows, School of Mechanical Engineering and Automation, Harbin Institute of Technology, Shenzhen 518055, Guangdong
Interests: flow mechanics; lab on a chip; micro/nano sensor; micro/nano-heat transfer
Special Issues, Collections and Topics in MDPI journals
Prof. Xingyu Jiang

E-Mail Website
Guest Editor
Southern University of Science and Technology, Shenzhen, Guangdong 518055, China
Interests: analytical chemistry, microfluidics, biomedical engineering, nano/bio medicine
Prof. Carolyn Ren

E-Mail Website
Guest Editor
Department of Mechanical and Mechatronics Engineering, University of Waterloo, Waterloo, ON N2L 1W2, Canada
Interests: lab-on-a-chip; droplet microfluidics; computational fluid dynamics; protein separation and detection; soft lithography

Special Issue Information

Dear Colleagues,

The 3rd International Conference of Microfluidics, Nanofluidics, and Lab-on-a-Chip (ICMFLOC 2021) will be held in Shenzhen, China during 2-4 July 2021 2020. This conference is intended to provide a forum for researchers, educators, and practitioners around the world to exchange the most advanced scientific knowledge on research in microfluidics, nanofluidics, and lab-on-a-chip technology, and to inspire new efforts to expand the frontiers of these research and development. Specific topics include but are not limited to the following:

  1. Fundamentals in Micro and Nanoflows
  2. Droplets, Bubbles and Digital Microfluidics
  3. Electrokinetic Flows
  4. Single Cell Analysis
  5. Detection and Sensing Techniques
  6. Applications of Lab on a Chip
  7. Optofluidics, Acoustic Fluidics, and Magnetic Fluidics
  8. Particles, Cells and Organisms
  9. Sample Processing and Separation
  10. Heat and Mass Transfer at Micro and Nano Scales
  11. Organ on a Chip and Drug Screening
  12. Micro and Nanoengineering
  13. Commercialization of Lab on a Chip Technologies

This Special Issue will publish selected papers from ICMFLOC 2021. These papers will be peer-reviewed for the validation of research results, developments, and applications. In addition, submissions from others that are not associated with this conference but with themes focusing on microfluidics, nanofluidics, and lab-on-a-chip technology are also welcome.

Prof. Yonggang Zhu
Prof. Xingyu Jiang
Prof. Carolyn Ren
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Micromachines is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Published Papers (2 papers)

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Research

14 pages, 6378 KiB  
Article
Microparticle Transport and Sedimentation in a Rhythmically Expanding Alveolar Chip
by Wei Zhang, Jun Dong, Huimin Lv, Weitao Bai, Hongzhou Lu, Bernd R. Noack, Yonggang Zhu and Yue Yang
Micromachines 2022, 13(3), 485; https://0-doi-org.brum.beds.ac.uk/10.3390/mi13030485 - 20 Mar 2022
Cited by 4 | Viewed by 2014
Abstract
Understanding the mechanism of particle transport and sedimentation in pulmonary alveolus is important for deciphering the causes of respiratory diseases and helping the development of drug delivery. In this study, taking advantage of the microfluidic technique, an experimental platform was developed to study [...] Read more.
Understanding the mechanism of particle transport and sedimentation in pulmonary alveolus is important for deciphering the causes of respiratory diseases and helping the development of drug delivery. In this study, taking advantage of the microfluidic technique, an experimental platform was developed to study particle behavior in a rhythmically expanding alveolar chip for a sufficient number of cycles. The alveolar flow patterns at different generations were measured for two cases with the gravity direction parallel or vertical to the alveolar duct. Affected by both the vortex flow inside the alveoli and the shear flow in the duct simultaneously, it was observed that particles inside the alveoli either escaped from the inlet of the alveolar duct or stayed in the alveoli, revealing the irreversibility of particle transport in the alveoli. At the earlier acinar generations, particles were inclined to deposit on the distal alveolar wall. The settling rates of particles of different sizes in the alveoli were also compared. This study provides valuable data for understanding particle transport and sedimentation in the alveoli. Full article
(This article belongs to the Special Issue Selected Papers from the 3rd International Conference of Microfluidics, Nanofluidics and Lab-on-a-Chip)
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17 pages, 6326 KiB  
Article
Enhancement of Binding Kinetics on Affinity Substrates Using Asymmetric Electroosmotic Flow on a Sinusoidal Bipolar Electrode
by Yupan Wu, Bowen Hu, Xun Ma, Yucheng Wang, Wei Li and Shaoxi Wang
Micromachines 2022, 13(2), 207; https://0-doi-org.brum.beds.ac.uk/10.3390/mi13020207 - 28 Jan 2022
Cited by 5 | Viewed by 1425
Abstract
In the context of the COVID-19 epidemic, enhancing the transport of analyte to a sensor surface is crucial for rapid detection of biomolecules since common conditions, including low diffusion coefficients, cause inordinately long detection times. Integrated microfluidic immunoassay chips are receiving increasing attention [...] Read more.
In the context of the COVID-19 epidemic, enhancing the transport of analyte to a sensor surface is crucial for rapid detection of biomolecules since common conditions, including low diffusion coefficients, cause inordinately long detection times. Integrated microfluidic immunoassay chips are receiving increasing attention for their low sample volume and fast response time. We herein take advantage of asymmetric ICEO flow at a bipolar sinusoidal electrode to improve the rate of antibody binding to the reaction surface based on finite element modeling. Three different microfluidic cavities are proposed by changing the positions of the surface reaction area. We further investigate the relationship between binding enhancement and reaction surface positions, Damkohler number, and the voltage and frequency of the AC signal applied to the driving electrodes. Furthermore, the influence of the AC signal applied to the sinusoidal bipolar electrode on antigen–antibody-binding performance is studied in detail. Above all, the simulation results demonstrate that the microfluidic immune-sensor with a sinusoidal bipolar electrode could not only significantly improve the heterogeneous immunoassays but also enable efficient enhancement of assays in a selected reaction region within the micro-cavity, providing a promising approach to a variety of immunoassay applications, such as medical diagnostics and environmental and food monitoring. Full article
(This article belongs to the Special Issue Selected Papers from the 3rd International Conference of Microfluidics, Nanofluidics and Lab-on-a-Chip)
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